Engineering protein and peptide-based materials for drug delivery applications has gained
momentum due to their biochemical and biophysical properties over synthetic materials …

Proteins and peptides have played a pivotal role in revolutionizing disease treatment over
the last century. Despite their commercial success, protein therapeutics can be eliminated or …

Protein pharmaceuticals have become a significant class of marketed drug products and are
expected to grow steadily over the next decade. Development of a commercial protein …

PASylation® technology comprises the conjugation–via genetic fusion or chemical coupling–
of pharmacologically active compounds, such as proteins, peptides and low molecular …

Protein–polymer conjugates are increasingly being applied in biomedicine because of the
unique combination of the biological activity of the proteins and the multifunctionality and …

Protein therapeutics have gained momentum in recent years and become a pillar in treating
many diseases and the only choice in several ailments. Protein therapeutics are highly …

PASylation, which was recently reported as the conjugation of pharmacologically active
compounds with polypeptide sequences mainly made of proline, alanine and serine, has …

The final goal in recombinant protein production is to obtain high-quality pure protein
samples. Indeed, the successful downstream application of a recombinant protein depends …

PAS polypeptides comprise long repetitive sequences of the small L‐amino acids proline,
alanine and/or serine that were developed to expand the hydrodynamic volume of …

Although polyethylene glycol (PEG), or “PEGylation” has become a widely applied approach
for improving the efficiency of drug delivery, the immunogenicity and non-biodegradability of …