The immunology of systemic lupus erythematosus
GC Tsokos - Nature Immunology, 2024 - nature.com
Understanding the pathogenesis and clinical manifestations of systemic lupus
erythematosus (SLE) has been a great challenge. Reductionist approaches to understand …
erythematosus (SLE) has been a great challenge. Reductionist approaches to understand …
Systemic lupus erythematosus genetics: insights into pathogenesis and implications for therapy
Y Ghodke-Puranik, M Olferiev, MK Crow - Nature Reviews …, 2024 - nature.com
Systemic lupus erythematosus (SLE) is a prime example of how the interplay between
genetic and environmental factors can trigger systemic autoimmunity, particularly in young …
genetic and environmental factors can trigger systemic autoimmunity, particularly in young …
Monogenic lupus: insights into disease pathogenesis and therapeutic opportunities
Y Qin, J Ma, CG Vinuesa - Current opinion in rheumatology, 2024 - journals.lww.com
Monogenic lupus: insights into disease pathogenesis and ther... : Current Opinion in
Rheumatology Monogenic lupus: insights into disease pathogenesis and therapeutic …
Rheumatology Monogenic lupus: insights into disease pathogenesis and therapeutic …
Whole exome sequencing in patients with childhood‐onset systemic lupus erythematosus: Results from a Croatian national study
The purpose of this study was to identify new and low‐frequency gene variants using whole
exome sequencing (WES) in patients with childhood‐onset systemic lupus erythematosus …
exome sequencing (WES) in patients with childhood‐onset systemic lupus erythematosus …
自身免疫性肝病患者SH2B3 基因Rs3184504 单核苷酸多态性分析
陈大同， 岳展伊， 张小蓬 - 实用肝脏病杂志, 2024 - manu43.magtech.com.cn
目的探讨自身免疫性肝病(AILD) 患者SH2B 衔接蛋白3 (SH2B3) 基因中Rs3184504
单核苷酸多态性(SNP) 变化. 方法2017 年6 月~ 2023 年10 月我院收治的58 …
单核苷酸多态性(SNP) 变化. 方法2017 年6 月~ 2023 年10 月我院收治的58 …
Reduced function of the adaptor SH2B3 promotes T1D via altered γc cytokine-regulated, T cell intrinsic immune tolerance
TK Watson, ABI Rosen, T Drow, JA Medjo… - bioRxiv, 2024 - biorxiv.org
Genome-wide association studies have identified SH2B3 as an important non-MHC gene for
islet autoimmunity and type 1 diabetes (T1D). In this study, we found a single SH2B3 …
islet autoimmunity and type 1 diabetes (T1D). In this study, we found a single SH2B3 …
HNF-1β alleviates podocyte injury in lupus nephritis by maintaining endoplasmic reticulum homeostasis
H Zou, J Yu, Y Ruan, Y Xie, X An, P Chen… - Lupus Science & …, 2024 - lupus.bmj.com
Objective The current study aims to elucidate the critical function of hepatocyte nuclear factor
1-beta (HNF1-β) in lupus nephritis (LN) by investigating its modulation of the Derlin …
1-beta (HNF1-β) in lupus nephritis (LN) by investigating its modulation of the Derlin …