Pathophysiology of eosinophilic esophagitis

KM O'Shea, SS Aceves, ES Dellon, SK Gupta… - Gastroenterology, 2018 - Elsevier
Eosinophilic esophagitis is an emerging disease that is distinguished from
gastroesophageal reflux disease by the expression of a unique esophageal transcriptome …

Type 2 inflammation in eosinophilic esophagitis: from pathophysiology to therapeutic targets

F Racca, G Pellegatta, G Cataldo, E Vespa… - Frontiers in …, 2022 - frontiersin.org
Eosinophilic esophagitis (EoE) is a chronic immune-mediated disease of the esophagus
characterized clinically by symptoms related to esophageal dysfunction and histologically by …

Mechanistic insights into eosinophilic esophagitis: therapies targeting pathophysiological mechanisms

S Massironi, G Mulinacci, C Gallo, A Elvevi, S Danese… - Cells, 2023 - mdpi.com
Eosinophilic esophagitis (EoE) is a chronic inflammatory disease characterized by
eosinophilic infiltration of the esophagus. It arises from a complex interplay of genetic …

Minimally invasive biomarker studies in eosinophilic esophagitis: a systematic review

BT Hines, MA Rank, BL Wright, LA Marks… - Annals of Allergy …, 2018 - Elsevier
Abstract Background Eosinophilic esophagitis (EoE) is a chronic, inflammatory disease of
the esophagus that currently requires repeated endoscopic biopsies for diagnosis and …

Pathophysiology of eosinophilic esophagitis

BP Davis - Clinical reviews in allergy & immunology, 2018 - Springer
Eosinophilic esophagitis (EoE) is a chronic inflammatory disease of the esophagus
associated with an atopic predisposition which appears to be increasing in prevalence over …

Pharmacotherapies for the treatment of eosinophilic esophagitis: state of the art review

WE de Rooij, ES Dellon, CE Parker, BG Feagan… - Drugs, 2019 - Springer
Eosinophilic esophagitis (EoE), a chronic allergic disorder of the esophagus, is
characterized by symptoms of esophageal dysfunction and eosinophil-predominant …

IL-15 regulates fibrosis and inflammation in a mouse model of chronic pancreatitis

M Manohar, HK Kandikattu… - American Journal of …, 2018 - journals.physiology.org
Pancreatitis is an inflammatory disease characterized by the induction of several
proinflammatory cytokines like interleukin (IL)-6, IL-8, IL-1β, and IL-1. Recently, the …

ACG clinical guideline: Diagnosis and management of eosinophilic esophagitis

ES Dellon, AB Muir, DA Katzka, SC Shah… - Official journal of the …, 2025 - journals.lww.com
Eosinophilic esophagitis (EoE) is a chronic immune-mediated disease of the esophagus. It
is diagnosed in the setting of symptoms of esophageal dysfunction and an eosinophilic …

Molecular basis and cellular mechanisms of eosinophilic esophagitis for the clinical practice

Á Arias, AJ Lucendo - Expert Review of Gastroenterology & …, 2019 - Taylor & Francis
ABSTRACT Introduction: Eosinophilic esophagitis (EoE) is a chronic, allergen-driven
inflammatory esophageal disease characterized by predominantly eosinophilic inflammation …

Mononuclear cell composition and activation in blood and mucosal tissue of eosinophilic esophagitis

E Gruden, M Kienzl, D Ristic, O Kindler… - Frontiers in …, 2024 - frontiersin.org
Introduction Eosinophilic esophagitis (EoE) is a chronic, inflammatory, antigen-driven
disease of the esophagus. Tissue EoE pathology has previously been extensively …