Nutraceuticals/drugs promoting mitophagy and mitochondrial biogenesis may combat the mitochondrial dysfunction driving progression of dry age-related macular …

LM Lewis Luján, MF McCarty, JJ Di Nicolantonio… - Nutrients, 2022 - mdpi.com
In patients with age-related macular degeneration (AMD), the crucial retinal pigment
epithelial (RPE) cells are characterized by mitochondria that are structurally and functionally …

An update on the review of microbial synthesis of glucosamine and N-acetylglucosamine

Y Yang, J Wang, M Yao, X Li, X Lu, J He… - World Journal of …, 2023 - Springer
Glucosamine (GlcN) is a natural amino monosaccharide in which a hydroxyl group of
glucose is substituted by an amino group. It belongs to functional amino sugar compounds …

No associations between glucosamine supplementation and dementia or Parkinson's disease: Findings from a large prospective cohort study

B Ai, L Chen, M Cai, J Fu, H Li, H Lin… - The Journals of …, 2024 - academic.oup.com
Background We investigated the associations between habitual use of glucosamine and
incident dementia and Parkinson's disease in a population-based cohort. Methods Using the …

Hexosamine pathway activation improves memory but does not extend lifespan in mice

K Allmeroth, MD Hartman, M Purrio, A Mesaros… - Aging …, 2022 - Wiley Online Library
Glucosamine feeding and genetic activation of the hexosamine biosynthetic pathway (HBP)
have been linked to improved protein quality control and lifespan extension. However, as an …