The microbiome: an integral player in immune homeostasis and inflammation in the respiratory tract

O Perdijk, R Azzoni, BJ Marsland - Physiological Reviews, 2024 - journals.physiology.org
The last decade of microbiome research has highlighted its fundamental role in systemic
immune and metabolic homeostasis. The microbiome plays a prominent role during …

Acute rejection in the modern lung transplant era

B Renaud-Picard, A Koutsokera… - … in Respiratory and …, 2021 - thieme-connect.com
Acute cellular rejection (ACR) remains a common complication after lung transplantation.
Mortality directly related to ACR is low and most patients respond to first-line …

Lung allograft microbiome association with gastroesophageal reflux, inflammation, and allograft dysfunction

PHH Schneeberger, CYK Zhang, J Santilli… - American Journal of …, 2022 - atsjournals.org
Rationale: It remains unclear how gastroesophageal reflux disease (GERD) affects allograft
microbial community composition in lung transplant recipients and its impact on lung …

Lung allograft dysfunction: does aspiration hold the key?

AA Pragman - American Journal of Respiratory and Critical Care …, 2022 - atsjournals.org
2012; 186: 536–545. 10. Sharma NS, Wille KM, Athira S, Zhi D, Hough KP, Diaz-Guzman E,
et al. Distal airway microbiome is associated with immunoregulatory myeloid cell responses …

[HTML][HTML] Ineffective esophageal motility is associated with acute rejection after lung transplantation independent of gastroesophageal reflux

WK Lo, B Hiramoto, HJ Goldberg… - World Journal of …, 2023 - ncbi.nlm.nih.gov
BACKGROUND Gastroesophageal reflux is associated with poorer outcomes after lung
transplant, likely through recurrent aspiration and allograft injury. Although prior studies …

Stanovení žlučových kyselin v bronchoalveolární laváži pacientů po transplantaci plic

D Plášilová - 2024 - dspace.cuni.cz
Transplantace plic je život zachraňující metodou léčby pro pacienty trpícím plicním selháním.
Medián přežití pacientů po tomto zákroku je ovšem stále nízký (6 let). Hlavním důvodem je …