Metabolic syndrome (MetS) is a complex of diseases that lead to mortality due to the
development of cardiovascular problems. Quercetin, as an important flavonoid, has various …

Hypertension is the most common chronic disease in the world, yet the precise cause of
elevated blood pressure often cannot be determined. Animal models have been useful for …

Men have higher blood pressure than women through much of life regardless of race and
ethnicity. This is a robust and highly conserved sex difference that it is also observed across …

Sex and gender differences are of fundamental importance in most diseases, including
chronic kidney disease (CKD). Men and women with CKD differ with regard to the …

Plasminogen activator inhibitor 1 (PAI-1) is a member of the serine protease inhibitor
(serpin) superfamily. PAI-1 is the principal inhibitor of the plasminogen activators, tissue …

The high renal oxygen (O2) demand is associated primarily with tubular O2 consumption
(Qo2) necessary for solute reabsorption. Increasing O2 delivery relative to demand via …

The blood pressure lowering effect of a fruit and vegetable-rich diet is a necessary dietary
lifestyle measure now included the guidelines for the management of arterial hypertension …

The overall production of nitric oxide (NO) is decreased in chronic kidney disease (CKD)
which contributes to cardiovascular events and further progression of kidney damage. There …

This review focuses on the effects of thyroid hormones in vascular and renal systems.
Special emphasis is given to the mechanisms by which thyroid hormones affect the …

In the United States the prevalence of end-stage renal disease (ESRD) reached epidemic
proportions in 2012 with over 600,000 patients being treated. The rates of ESRD among the …