Introduction Animal models are widely used in glaucoma-related research. Since the
elevated intraocular pressure (IOP) is a major risk factor underlying the disease …

Modeling complex eye diseases like age-related macular degeneration (AMD) and
glaucoma poses significant challenges, since these conditions depend highly on age …

As part of the central nervous system, the optic nerve, composed of axons from retinal
ganglion cells (RGCs), generally fails to regenerate on its own when injured in adult …

Vision depends on accurate signal conduction from the retina to the brain through the optic
nerve, an important part of the central nervous system that consists of bundles of axons …

Glaucoma is a major global health concern and the leading cause of irreversible blindness
worldwide, characterized by the progressive degeneration of retinal ganglion cells (RGCs) …

The macromolecular architecture of strands and cross-links in a polymer network plays an
indispensable role in determining its properties, such as elasticity, network dynamics, and …

The molecular mechanism of how reduced mobile zinc (Zn 2+) affected retinal ganglion cell
(RGC) survival and optic nerve regeneration after optic nerve crush (ONC) injury remains …

Retinal ischaemia/reperfusion (I/R) injury is a common cause of retinal ganglion cell (RGC)
apoptosis and axonal degeneration, resulting in irreversible visual impairment. However …

视力取决于从视网膜经视神经准确传导到大脑的信号, 而视神经是由源自视网膜神经节细胞的轴
突束所组成. 哺乳动物视神经作为中枢神经系统的重要组成部分, 一旦受伤就不能再生 …

Adipose derived stem cells (ADSCs) have the potential to attenuate osteoarthritis (OA);
however, complications such as immune rejection and tumour formation limit their …