Imaging and fluid biomarkers in frontotemporal dementia

LH Meeter, LD Kaat, JD Rohrer… - Nature Reviews …, 2017 - nature.com
Frontotemporal dementia (FTD), the second most common type of presenile dementia, is a
heterogeneous neurodegenerative disease characterized by progressive behavioural …

Radiological biomarkers for diagnosis in PSP: where are we and where do we need to be?

JL Whitwell, GU Höglinger, A Antonini… - Movement …, 2017 - Wiley Online Library
ABSTRACT PSP is a pathologically defined neurodegenerative tauopathy with a variety of
clinical presentations including typical Richardson's syndrome and other variant PSP …

Clinical, anatomical, and pathological features in the three variants of primary progressive aphasia: a review

M Montembeault, SM Brambati… - Frontiers in …, 2018 - frontiersin.org
Primary progressive aphasias (PPA) are neurodegenerative diseases clinically
characterized by an early and relatively isolated language impairment. Three main clinical …

[HTML][HTML] FDG-PET and CSF biomarker accuracy in prediction of conversion to different dementias in a large multicentre MCI cohort

SP Caminiti, T Ballarini, A Sala, C Cerami, L Presotto… - NeuroImage: Clinical, 2018 - Elsevier
Background/aims In this multicentre study in clinical settings, we assessed the accuracy of
optimized procedures for FDG-PET brain metabolism and CSF classifications in predicting …

Effectiveness of language training and non-invasive brain stimulation on oral and written naming performance in Primary Progressive Aphasia: A meta-analysis and …

M Cotelli, R Manenti, C Ferrari, E Gobbi, A Macis… - Neuroscience & …, 2020 - Elsevier
The aim of this systematic review and meta-analysis is to examine the efficacy of language
training, alone or in combination with non-invasive brain stimulation techniques, designed to …

Differential diagnosis of apraxia of speech in children and adults: A scoping review

KM Allison, C Cordella, J Iuzzini-Seigel… - Journal of Speech …, 2020 - ASHA
Purpose Despite having distinct etiologies, acquired apraxia of speech (AOS) and childhood
apraxia of speech (CAS) share the same central diagnostic challenge (ie, isolating markers …

Gender differences in healthy aging and Alzheimer's Dementia: A 18F‐FDG‐PET study of brain and cognitive reserve

M Malpetti, T Ballarini, L Presotto… - Human brain …, 2017 - Wiley Online Library
Cognitive reserve (CR) and brain reserve (BR) are protective factors against age‐associated
cognitive decline and neurodegenerative disorders. Very limited evidence exists about …

Brain glucose metabolism in Lewy body dementia: implications for diagnostic criteria

SP Caminiti, A Sala, L Iaccarino, L Beretta… - Alzheimer's research & …, 2019 - Springer
Abstract Background [18F] FDG-PET hypometabolism patterns are indicative of different
neurodegenerative conditions, even from the earliest disease phase. This makes [18F] FDG …

Biomarkers for diseases with TDP-43 pathology

P Steinacker, P Barschke, M Otto - Molecular and Cellular Neuroscience, 2019 - Elsevier
The discovery that aggregated transactive response DNA-binding protein 43 kDa (TDP-43)
is the major component of pathological ubiquitinated inclusions in amyotrophic lateral …

Frontotemporal dementia–current concepts

GK Puppala, SP Gorthi, V Chandran… - Neurology …, 2021 - journals.lww.com
Frontotemporal dementia (FTD) is an entity that includes a group of neurodegenerative
disease with symptoms predominantly pertaining to deficits in behavior, executive function …