Rheumatoid arthritis (RA), a distressing inflammatory autoimmune disease, is managed
mainly by Disease-modifying antirheumatic drugs (DMARDs), eg leflunomide (LEF). LEF …

Cannabinoids: cannabidiol (CBD), cannabidiolic acid (CBDA), and cannabichromene (CBC)
are lipophilic compounds with limited water solubility, resulting in challenges related to their …

Transdermal drug delivery has been widely adopted as a plausible alternative to the oral
route of administration, especially for drugs with poor systemic bioavailability. The objective …

This study aims to compare the potential of Polyethylene glycol (PEG‐free and PEG‐based
self‐emulsifying drug delivery systems (SEDDS) for the oral administration of insulin …

Composite bio-based hydrogels have been obtaining a significant attention in recent years
as one of the most promising drug delivery systems. In the present study, the preparation of …

Objective Antibiotic utilization stands as the strongest modifiable determinant for
Clostridioides difficile infection (CDI). However, previous studies have relied on aggregated …

Neratinib maleate (NM), a tyrosine kinase inhibitor, is used in the treatment of breast cancer.
NM is orally administered at a high dose of 290 mg due to its low solubility and poor …

Abstract Treatment therapies used to manage osteoporosis are associated with severe side
effects. So worldwide herbs are widely studied to develop alternative safe & effective …

In an endeavor to ameliorate the solubility and subsequent oral bioavailability of Cefixime
(CEF), a drug noted for its deficient water solubility, the formulation of ternary inclusion …

Tenofovir (TNF) is a common component of many antiretroviral therapy regimens, but it is
associated with poor membrane permeability and low oral bioavailability. To improve its oral …