Casein kinase 2 (CK2): A possible therapeutic target in acute myeloid leukemia

Ø Bruserud, H Reikvam - Cancers, 2023 - mdpi.com
Simple Summary Acute myeloid leukemia (AML) is an aggressive blood cancer disease that
can only be cured by intensive anticancer treatment, and for several patients, allogeneic …

Recent advance of clinically approved small-molecule drugs for the treatment of myeloid leukemia

ZX Niu, YT Wang, JF Sun, P Nie, P Herdewijn - European Journal of …, 2023 - Elsevier
Myeloid leukemia denotes a hematologic malignancy characterized by aberrant proliferation
and impaired differentiation of blood progenitor cells within the bone marrow. Despite the …

Sorafenib plus triplet therapy with venetoclax, azacitidine and homoharringtonine for refractory/relapsed acute myeloid leukemia with FLT3‐ITD: A multicenter phase …

S Yu, Y Zhang, G Yu, Y Wang, R Shao… - Journal of Internal …, 2024 - Wiley Online Library
Background Patients with relapsed or refractory acute myeloid leukemia (R/R AML) and
FLT3‐internal tandem duplication (FLT3‐ITD) respond infrequently to salvage …

Ferroptosis-Related Gene Signature for Prognosis Prediction in Acute Myeloid Leukemia and Potential Therapeutic Options

Y Hong, Q Liu, C Xin, H Hu, Z Zhuang… - … Journal of General …, 2024 - Taylor & Francis
Background Limited data were available to understand the significance of ferroptosis in
leukemia prognosis, regardless of the genomic background. Methods RNA-seq data from …

FLAG/FLAG-Ida Regimen in Secondary and Relapsed/Refractory Acute Myeloid Leukemia—Even in the Era of New Treatment Modalities Still a Significant Player

S Anžej Doma, M Sever, G Jakoš… - Journal of Clinical …, 2024 - mdpi.com
(1) Background: Relapsed/refractory (r/r) and secondary acute myeloid leukemia are
highlighted by chemoresistance and poor outcomes. The aim of the study was to assess the …

Outcomes of adults with refractory or relapsed acute myeloid leukemia treated with azacitidine and venetoclax compared to other therapies: a multicenter retrospective …

AA Pelland, X Deschênes-Simard, X Savard… - Leukemia & …, 2024 - Taylor & Francis
This study reports characteristics and outcomes of adults who received Azacitidine-
Venetoclax (AZA-VEN) compared to other salvage therapies (NO-AZA-VEN) as first salvage …

[HTML][HTML] The Outcome of Outpatient Intermediate and High Dose Cytarabine Consolidation Chemotherapy in Patients with Acute Myeloid Leukemia. The Experience of …

KA Al-Anazi, NJ Alsaeed, S Kanfer… - Journal of Stem …, 2024 - stemcelltherjournal.com
Background: Adult patients with Acute Myeloid Leukemia (AML) have traditionally been
hospitalized for the duration of intensive consolidation chemotherapy until blood count …

[HTML][HTML] Anti-CD22 Calicheamicin-Inotuzumab Ozogamicin Combined with Venetoclax+ Azacitidine in the Treatment of Mixed-Phenotype Acute Leukemia: A Case …

K Li, Y Wang, R Pei, Y Lu, J Cao… - Turkish Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Anti-CD22 Calicheamicin-Inotuzumab Ozogamicin Combined with Venetoclax + Azacitidine in
the Treatment of Mixed-Phenotype Acute Leukemia: A Case Report - PMC Skip to main content …

[PDF][PDF] Venetoclax-Azacitidine Salvage Chemotherapy in Relapsed/Refractory Acute Myeloid Leukemia and Myelodysplastic Syndrome: A Single-Center Experience

D Osman, ML Maroto, F Kinsella… - Journal of Hematology, 2024 - jh.elmerpub.com
Acute myeloid leukemia (AML) is a malignant bone marrow disorder arising from early
myeloid progenitors leading to clonal expansion and myeloid maturation arrest [1]. It is the …

[PDF][PDF] Anti-CD22 Calecheamicin-Inotuzumab Ozogamicin Combined with Venetoclax+ Azatabine in the Treatment of Mixed Phenotype Acute Leukemia: A Case …

K Li - 2024 - jag.journalagent.com
A 57-year-old patient was diagnosed with MLAL by presenting hyperleukocytosis and
anemia. Bone marrow morphology test presents 86% lymphoid blasts. Flow cytometry …