Abstract Alcohol Use Disorder (AUD) affects around 14.5 million individuals in the United
States, with Substance Use Disorder (SUD) affecting an additional 8.3 million individuals …

Our urge to sleep increases with time spent awake, until sleep becomes inescapable. The
sleep following sleep deprivation is longer and deeper, with an increased power of delta …

Active responses to stressors involve motor planning, execution, and feedback. Here we
identify an insular cortex to BNST (insula→ BNST) circuit recruited during restraint stress …

The bed nucleus of the stria terminalis (BNST) is a critical mediator of stress responses and
anxiety-like behaviors. Neurons expressing protein kinase C delta (BNSTPKCδ) are an …

The novel peptide phoenixin was shown to be involved in several physiological processes
ranging from reproduction to food intake. Interest in this protein has steadily increased over …

Excitatory signaling mediated by NMDARs has been shown to regulate mood disorders.
However, current treatments targeting NMDAR subtypes have shown limited success in …

Non-selective antagonists of metabotropic glutamate receptor subtypes 2 (mGlu 2) and 3
(mGlu 3) exert rapid antidepressant-like effects by enhancing prefrontal cortex (PFC) …

Chronic cocaine exposure induces enduring neuroadaptations that facilitate motivated drug
taking. Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are known to …

Sudden unexpected death in epilepsy (SUDEP) is the leading cause of death in refractory
epilepsy patients. Accumulating evidence from recent human studies and animal models …

Studies demonstrate a role for the bed nucleus of the stria terminalis (BNST) in modulating
affective behavior and stress-reward integration. To explore the dynamic nature of in vivo …