LM de Boer, AOJ Oorthuys, A Wiegman… - European journal of …, 2022 - academic.oup.com
Abstract Aims Lipoprotein (a)[Lp (a)] is a causal and independent risk factor for cardiovascular disease (CVD). People with elevated Lp (a) are often prescribed statins as …
TA Jacobson, KC Maki, CE Orringer, PH Jones… - Journal of clinical …, 2015 - Elsevier
Abstract An Expert Panel convened by the National Lipid Association previously developed a consensus set of recommendations for the patient-centered management of dyslipidemia …
AG Semb, E Ikdahl, G Wibetoe, C Crowson… - Nature Reviews …, 2020 - nature.com
Patients with rheumatoid arthritis (RA) are at high risk of developing cardiovascular disease (CVD). Inflammation has a pivotal role in the pathogenesis of CVD. RA is an inflammatory …
C Baigent, MJ Landray, C Reith, J Emberson… - The Lancet, 2011 - thelancet.com
Background Lowering LDL cholesterol with statin regimens reduces the risk of myocardial infarction, ischaemic stroke, and the need for coronary revascularisation in people without …
SM Grundy, JI Cleeman, CNB Merz, HB Brewer Jr… - Circulation, 2004 - Am Heart Assoc
The Adult Treatment Panel III (ATP III) of the National Cholesterol Education Program issued an evidence-based set of guidelines on cholesterol management in 2001. Since the …
PD Thompson, P Clarkson, RH Karas - Jama, 2003 - jamanetwork.com
Statins (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors) are associated with skeletal muscle complaints, including clinically important myositis and rhabdomyolysis, mild …
JJP Kastelein, F Akdim, ESG Stroes… - … England Journal of …, 2008 - Mass Medical Soc
Background Ezetimibe, a cholesterol-absorption inhibitor, reduces levels of low-density lipoprotein (LDL) cholesterol when added to statin treatment. However, the effect of …
M Garcia-Calvo, JM Lisnock, HG Bull… - Proceedings of the …, 2005 - National Acad Sciences
Ezetimibe is a potent inhibitor of cholesterol absorption that has been approved for the treatment of hypercholesterolemia, but its molecular target has been elusive. Using a …