SARS-CoV-2 specific memory T cell epitopes identified in COVID-19-recovered subjects
The COVID-19 pandemic caused by SARS-CoV-2 infection poses a serious threat to public
health. An explicit investigation of COVID-19 immune responses, particularly the host …
health. An explicit investigation of COVID-19 immune responses, particularly the host …
In silico formulation of a next-generation multiepitope vaccine for use as a prophylactic candidate against Crimean-Congo hemorrhagic fever
Abstract Background Crimean-Congo hemorrhagic fever (CCHF) is a widespread disease
transmitted to humans and livestock animals through the bite of infected ticks or close …
transmitted to humans and livestock animals through the bite of infected ticks or close …
Designing of potential polyvalent vaccine model for respiratory syncytial virus by system level immunoinformatics approaches
STQ Naqvi, M Yasmeen, M Ismail… - BioMed Research …, 2021 - Wiley Online Library
Background. Respiratory syncytial virus (RSV) infection is a public health epidemic, leading
to around 3 million hospitalization and about 66,000 deaths each year. It is a life‐threatening …
to around 3 million hospitalization and about 66,000 deaths each year. It is a life‐threatening …
Computational design of immunogenic peptide constructs comprising multiple human leukocyte antigen restricted dengue virus envelope epitopes
N Kaushal, S Jain, M Baranwal - Journal of Molecular …, 2022 - Wiley Online Library
Dengue virus (DENV) is endemic in 100 countries with the ability to impact nearly 50% of
world population. DENV envelope (E) protein is responsible for viral attachment to host cells …
world population. DENV envelope (E) protein is responsible for viral attachment to host cells …
Exploring SARS-COV-2 structural proteins to design a multi-epitope vaccine using immunoinformatics approach: An in silico study
S Sanami, M Alizadeh, M Nosrati, KA Dehkordi… - Computers in Biology …, 2021 - Elsevier
In December 2019, a new virus called SARS-CoV-2 was reported in China and quickly
spread to other parts of the world. The development of SARS-COV-2 vaccines has recently …
spread to other parts of the world. The development of SARS-COV-2 vaccines has recently …
Employing computational tools to design a multi-epitope vaccine targeting human immunodeficiency virus-1 (HIV-1)
Background Despite being in the 21st century, the world has still not been able to vanquish
the global AIDS epidemic, and the only foreseeable solution seems to be a safe and …
the global AIDS epidemic, and the only foreseeable solution seems to be a safe and …
Identification of conserved immunogenic peptides of SARS-CoV-2 nucleocapsid protein
J Verma, N Kaushal, M Manish… - Journal of …, 2024 - Taylor & Francis
The emergence of the new SARS-CoV-2 variants has led to major concern regarding the
efficacy of approved vaccines. Nucleocapsid is a conserved structural protein essential for …
efficacy of approved vaccines. Nucleocapsid is a conserved structural protein essential for …
Mapping potential vaccine candidates predicted by VaxiJen for different viral pathogens between 2017–2021—a scoping review
Reverse vaccinology (RV) is a promising alternative to traditional vaccinology. RV focuses
on in silico methods to identify antigens or potential vaccine candidates (PVCs) from a …
on in silico methods to identify antigens or potential vaccine candidates (PVCs) from a …
Computational identification of a multi-peptide vaccine candidate in E2 glycoprotein against diverse hepatitis c virus genotypes
Abstract Hepatitis C Virus (HCV) is estimated to affect nearly 180 million people worldwide,
culminating in∼ 0.7 million yearly casualties. However, a safe vaccine against HCV is not …
culminating in∼ 0.7 million yearly casualties. However, a safe vaccine against HCV is not …
Molecular dynamics simulation based prediction of T-cell epitopes for the production of effector molecules for liver cancer immunotherapy
S Zafar, Y Bai, SA Muhammad, J Guo, H Khurram… - PloS one, 2025 - journals.plos.org
Liver cancer is the sixth most frequent malignancy and the fourth major cause of deaths
worldwide. The current treatments are only effective in early stages of cancer. To overcome …
worldwide. The current treatments are only effective in early stages of cancer. To overcome …