Gene duplication is an important evolutionary mechanism allowing to provide new genetic
material and thus opportunities to acquire new gene functions for an organism, with major …

This article reviews the various models that have been used to describe the relationships
between gene trees and species trees. Molecular phylogeny has focused mainly on …

To connect human biology to fish biomedical models, we sequenced the genome of spotted
gar (Lepisosteus oculatus), whose lineage diverged from teleosts before teleost genome …

TNF-α is a cytokine involved in systemic inflammation and regulation of immune cells. It is
produced chiefly by activated macrophages as a membrane or secreted form. In rainbow …

Genomicus is a database and web-server dedicated to comparative genomics in
eukaryotes. Its main functionality is to graphically represent the conservation of genomic …

Teleost fish are the most diverse group of vertebrates and provide opportunities to study the
evolution of sex determination (SD) systems. Using genomic and functional analyses, we …

Ancestral sequence reconstruction is a fundamental aspect of molecular evolution studies
and can trace small-scale sequence modifications through the evolution of genomes and …

All vertebrates including human have evolved from an ancestor that underwent two rounds
of whole genome duplication (2R-WGD). In addition, teleost fish underwent an additional …

Changes in bone size and shape are defining features of many vertebrates. Here we use
genetic crosses and comparative genomics to identify specific regulatory DNA alterations …

Mitochondrial respiration is an energy producing process that involves the coordinated
action of several protein complexes embedded in the inner membrane to finally produce …