Drug nanocrystals have been used for a wide range of drug delivery platforms in the
pharmaceutical industry, especially for bioavailability enhancement of poorly water-soluble …

Nano-particles have been successfully and widely applied in many industrial applications.
The wet-type mechanical milling process is a popular method used to produce nano …

Nanoparticles can be produced by wet grinding in stirred‐media mills. In the lower
nanometer range a true grinding limit exists, where the transferred energy from the grinding …

Although heat is generated during the wet stirred media milling of drug suspensions, leading
to notable temperature rise, a comprehensive analysis of heat generation does not exist …

A method combined with mechanical milling (MM) and mechanical alloying (MA) was
performed to prepare nanocrystal Cu–Cr supersaturated solid solution from commercially …

Fine grinding in stirred media mills is an important process in mineral, chemical and
pharmaceutical industry. The stressing mechanism in these mills is grinding through …

Stirred media milling is frequently used to generate nanoparticles for industrial applications
such as paints, inks, and food or for the life sciences. Each product suspension has different …

Purpose Nanosuspensions have been used for enhancing the bioavailability of poorly
soluble drugs. This study explores the temperature evolution during their preparation in a …

We studied wet-milling kinetics of a drug in a stirred mill using a microhydrodynamic model
with various radial distribution functions (RDFs). An n th-order kinetics model was fitted to …

Although temperature can significantly affect the stability and degradation of drug
nanosuspensions, temperature evolution during the production of drug nanoparticles via wet …