Surgical outcomes in lesional and non-lesional epilepsy: a systematic review and meta-analysis

JF Téllez-Zenteno, LH Ronquillo, F Moien-Afshari… - Epilepsy research, 2010 - Elsevier
PURPOSES: To provide evidence-based quantitative summary estimates of seizure
outcomes in patients with non-lesional and lesional epilepsy treated with surgery, and to …

Hippocampal sclerosis—origins and imaging

K Malmgren, M Thom - Epilepsia, 2012 - Wiley Online Library
The association between hippocampal sclerosis (HS) and epilepsy has been known for
almost two centuries. For many years, HS was studied in postmortem series; however, since …

Early surgical therapy for drug-resistant temporal lobe epilepsy: a randomized trial

J Engel, MP McDermott, S Wiebe, JT Langfitt, JM Stern… - Jama, 2012 - jamanetwork.com
Context Despite reported success, surgery for pharmacoresistant seizures is often seen as a
last resort. Patients are typically referred for surgery after 20 years of seizures, often too late …

FDG-PET improves surgical outcome in negative MRI Taylor-type focal cortical dysplasias

F Chassoux, S Rodrigo, F Semah, F Beuvon, E Landre… - Neurology, 2010 - AAN Enterprises
Objective: To determine the diagnostic accuracy and prognostic value of 18FDG-PET in a
recent series of patients operated for intractable partial epilepsy associated with …

Advances in MRI for'cryptogenic'epilepsies

A Bernasconi, N Bernasconi, BC Bernhardt… - Nature reviews …, 2011 - nature.com
Nearly one-third of patients with focal epilepsy experience disabling seizures that are
refractory to pharmacotherapy. Drug-resistant focal epilepsy is, however, potentially curable …

Characteristics and surgical outcomes of patients with refractory magnetic resonance imaging–negative epilepsies

CG Bien, M Szinay, J Wagner, H Clusmann… - Archives of …, 2009 - jamanetwork.com
Objective To explore several characteristics of patients with pharmacoresistant epilepsy
without distinct lesions on magnetic resonance images (MRI−), who account for a relevant …

Stereoelectroencephalography in presurgical assessment of MRI-negative epilepsy

A McGonigal, F Bartolomei, J Régis, M Guye… - Brain, 2007 - academic.oup.com
According to most existing literature, the absence of an MRI lesion is generally associated
with poorer prognosis in resective epilepsy surgery. Delineation of the epileptogenic zone …

Long‐term seizure outcome after resective surgery in patients evaluated with intracranial electrodes

JC Bulacio, L Jehi, C Wong, J Gonzalez‐Martinez… - …, 2012 - Wiley Online Library
Purpose: Despite advances in “noninvasive” localization techniques, many patients with
medically intractable epilepsy require the placement of subdural (subdural grid electrode …

Type II focal cortical dysplasia: electroclinical phenotype and surgical outcome related to imaging

F Chassoux, E Landré, C Mellerio, B Turak… - …, 2012 - Wiley Online Library
Purpose: Type II focal cortical dysplasia (TTFCD), a highly epileptogenic lesion with severe
epilepsy curable by surgery, is missed by magnetic resonance imaging (MRI) in about one …

EEG-fMRI in the preoperative work-up for epilepsy surgery

M Zijlmans, G Huiskamp, M Hersevoort… - Brain, 2007 - academic.oup.com
Epilepsy surgery requires precise localization of the epileptic source. EEG-correlated
functional MRI (EEG-fMRI) is a new technique showing the haemodynamic effects of …