Classification and diagnosis of aggressive periodontitis

DH Fine, AG Patil, BG Loos - Journal of clinical periodontology, 2018 - Wiley Online Library
Objective Since the initial description of aggressive periodontitis (AgP) in the early 1900s,
classification of this disease has been in flux. The goal of this manuscript is to review the …

Periodontal health and disease: The contribution of genetics

LM Shaddox, LA Morford, L Nibali - Periodontology 2000, 2021 - Wiley Online Library
Periodontitis is an infectious, inflammatory disease that is associated with a complex
interplay between specific bacteria, host response, and environmental factors. Because of its …

A genome-wide association study identifies nucleotide variants at SIGLEC5 and DEFA1A3 as risk loci for periodontitis

M Munz, C Willenborg, GM Richter… - Human molecular …, 2017 - academic.oup.com
Periodontitis is one of the most common inflammatory diseases, with a prevalence of 11%
worldwide for the severe forms and an estimated heritability of 50%. The disease is …

Meta-analysis of genome-wide association studies of aggressive and chronic periodontitis identifies two novel risk loci

M Munz, GM Richter, BG Loos, S Jepsen… - European Journal of …, 2019 - nature.com
Periodontitis is one of the most common inflammatory diseases, with a prevalence of 11%
worldwide for the severe forms and an estimated heritability of 50%. It is classified into the …

What exactly distinguishes aggressive from chronic periodontitis: is it mainly a difference in the degree of bacterial invasiveness?

U Van der Velden - Periodontology 2000, 2017 - Wiley Online Library
Abstract At the International Workshop for Classification of Periodontal Diseases and
Conditions in 1999, the classification of aggressive and chronic periodontitis that is presently …

Genetics of periodontitis: discovery, biology, and clinical impact

AS Schaefer - Periodontology 2000, 2018 - Wiley Online Library
This review provides an update on genome‐wide association studies in periodontitis.
Studies in populations with European ancestry have dominated the landscape of …

Genetic polymorphisms and periodontal disease in populations of African descent: A review

PF Goncalves, TH Harris, T Elmariah… - Journal of …, 2018 - Wiley Online Library
Aggressive periodontitis is a rare but rapidly progressing form of periodontal disease that
usually affects otherwise systemically healthy individuals, at a young age. It usually affects …

Identification of genetic risk factors of aggressive periodontitis using genomewide association studies in association with those of chronic periodontitis

R Masumoto, J Kitagaki, C Fujihara… - Journal of …, 2019 - Wiley Online Library
To identify the genetic risk factors for aggressive periodontitis (AgP), it is important to
understand the progression and pathogenesis of AgP. The purpose of this review was to …

The Collaborative Cross mouse model for dissecting genetic susceptibility to infectious diseases

H Abu Toamih Atamni, A Nashef, FA Iraqi - Mammalian Genome, 2018 - Springer
Infectious diseases, also known as communicable diseases, refer to a full range of maladies
caused by pathogen invasion to the host body. Host response towards an infectious …

Roles of the Chr.9p21.3 ANRIL Locus in Regulating Inflammation and Implications for Anti-Inflammatory Drug Target Identification

G Aarabi, T Zeller, G Heydecke, M Munz… - Frontiers in …, 2018 - frontiersin.org
Periodontitis (PD) is a common gingival infectious disease caused by an over-aggressive
inflammatory reaction to dysbiosis of the oral microbiome. The disease induces a profound …