Mesocotical dopamine (DA) inputs to the prefrontal cortex (PFC) play a crtical role in normal
cognitive process and neuropsychiatic pathologies. This DA input regulates aspects of …

A core component to corticolimbic circuitry is the GABAergic interneuron. Neuroanatomic
studies conducted over the past century have demonstrated several subtypes of interneuron …

The neurodevelopmental sequelae of early deprivation were examined by testing (N= 132)
8‐and 9‐year‐old children who had endured prolonged versus brief institutionalized rearing …

The prefrontal cortex (PFC) has long been known to be involved in the mediation of complex
behavioral responses. Considerable research efforts are directed towards refining the …

Research on dopamine lies at the intersection of sophisticated theoretical and
neurobiological approaches to learning and memory. Dopamine has been shown to be …

Mesocorticolimbic dopamine circuity undergoes a protracted maturation during adolescent
life. Stable adult levels of behavioral functioning in reward, motivational, and cognitive …

Adolescence is a transitional period during development that is associated with a greater
likelihood of addiction to drugs than any other age. In the prefrontal cortex (PFC), D1 …

A variety of observations have suggested that the dopamine and serotonin systems may
play a role in the pathophysiology and treatment of major mental disorders of childhood …

The mesocorticolimbic dopamine system, which arises in the ventral tegmental area and
innervates the nucleus accumbens, among numerous other regions, has been implicated in …

Recent investigations have reported a reduced density of interneurons and an increase of
GABAA receptor binding occurring preferentially in layer II of the anterior cingulate cortex of …