The characteristic molecular composition of the different glycosaminoglycans (GAGs) is
related to their role as structural components and regulators of a multitude of functions of …

Glycosaminoglycans (GAGs) play a crucial role in tissue homeostasis by regulating the
activity and diffusion of bioactive molecules. Incorporating GAGs into biomaterials has …

Bioengineered soft tissues on any meaningful scale or complexity must incorporate aspects
of the functional tissue, namely a vasculature, providing cells oxygen and nutrients critical for …

Scarring of the vocal folds leads to a deterioration of the highly complex micro-structure with
consecutively impaired vibratory pattern and glottic insufficiency. The resulting dysphonia is …

Vocal folds are soft laryngeal connective tissues with distinct layered structures and complex
multicomponent matrix compositions that endow phonatory and respiratory functions. This …

Vocal fold scarring is a common cause of dysphonia. Current treatments involving vocal fold
augmentation do not yield satisfactory outcomes in the long term. Tissue engineering and …

Porous composite hydrogels were prepared using glycol chitosan as the matrix, glyoxal as
the chemical crosslinker, and carbon nanotubes (CNTs) as the fibers. Both carboxylic and …

Within the last decade, intensive research work has been conducted on thiolated hyaluronic
acids (HA-SH). By attaching sulfhydryl ligands onto naturally occurring hyaluronic acid …

Scars are a natural and unavoidable result from most wound repair procedures and the
body's physiological healing response. However, they scars can cause considerable …

The unique vibrational properties inherent to the human vocal fold have a significant
detrimental impact on wound healing and scar formation. Hydrogels have taken prominence …