Effects of strict prolonged bed rest on cardiorespiratory fitness: systematic review and meta-analysis

M Ried-Larsen, HM Aarts… - Journal of applied …, 2017 - journals.physiology.org
The aim of this systematic review and meta-analysis [International Prospective Register of
Systematic Reviews (PROSPERO) CRD42017055619] was to assess the effects of strict …

The detrimental effects of bedrest: Premature cardiovascular aging and dysfunction

CJ Mastrandrea, ET Hedge, RL Hughson - Canadian Journal of Cardiology, 2024 - Elsevier
Bedrest as an experimental paradigm or as an in-patient stay for medical reasons has
negative consequences for cardiovascular health. The effects of severe inactivity parallel …

[图书][B] Advanced environmental exercise physiology

SS Cheung, PN Ainslie - 2022 - books.google.com
Advanced Environmental Exercise Physiology, Second Edition, offers physiology students
and exercise science professionals a complete look at the major topics and debates in the …

Hypoxia aggravates inactivity-related muscle wasting

T Debevec, B Ganse, U Mittag, O Eiken… - Frontiers in …, 2018 - frontiersin.org
Poor musculoskeletal state is commonly observed in numerous clinical populations such as
chronic obstructive pulmonary disease (COPD) and heart failure patients. It, however …

PlanHab*: hypoxia does not worsen the impairment of skeletal muscle oxidative function induced by bed rest alone

D Salvadego, ME Keramidas, R Kölegård… - The Journal of …, 2018 - Wiley Online Library
Key points Superposition of hypoxia on 21 day bed rest did not worsen the impairment of
skeletal muscle oxidative function induced by bed rest alone. A significant impairment of …

Hypoxia and inactivity related physiological changes (constipation, inflammation) are not reflected at the level of gut metabolites and butyrate producing microbial …

R Šket, N Treichel, T Debevec, O Eiken… - Frontiers in …, 2017 - frontiersin.org
We explored the assembly of intestinal microbiota in healthy male participants during the run-
in (5 day) and experimental phases [21-day normoxic bed rest (NBR), hypoxic bedrest …

Systems View of Deconditioning During Spaceflight Simulation in the PlanHab Project: The Departure of Urine 1 H-NMR Metabolomes From Healthy State in Young …

R Šket, L Deutsch, Z Prevoršek, IB Mekjavić… - Frontiers in …, 2020 - frontiersin.org
We explored the metabolic makeup of urine in prescreened healthy male participants within
the PlanHab experiment. The run-in (5 day) and the following three 21-day interventions …

Substantial and reproducible individual variability in skeletal muscle outcomes in the cross-over designed planica bed rest program

R Fernandez-Gonzalo, AC McDonnell… - Frontiers in …, 2021 - frontiersin.org
To evaluate the individual responses in skeletal muscle outcomes following bed rest, data
from three studies (21-day PlanHab; 10-day FemHab and LunHab) were combined …

Hypoxia and inactivity related physiological changes precede or take place in absence of significant rearrangements in bacterial community structure: The PlanHab …

R Šket, N Treichel, S Kublik, T Debevec, O Eiken… - PloS one, 2017 - journals.plos.org
We explored the assembly of intestinal microbiota in healthy male participants during the
randomized crossover design of run-in (5 day) and experimental phases (21-day normoxic …

The importance of objective stool classification in fecal 1H-NMR metabolomics: exponential increase in stool crosslinking is mirrored in systemic inflammation and …

L Deutsch, B Stres - Metabolites, 2021 - mdpi.com
Past studies strongly connected stool consistency—as measured by Bristol Stool Scale
(BSS)—with microbial gene richness and intestinal inflammation, colonic transit time and …