[HTML][HTML] Automated live-cell single-molecule tracking in enteroid monolayers reveals transcription factor dynamics probing lineage-determining function

N Walther, S Anantakrishnan, TGW Graham, GM Dailey… - Cell Reports, 2024 - cell.com
Lineage transcription factors (TFs) provide one regulatory level of differentiation crucial for
the generation and maintenance of healthy tissues. To probe TF function by measuring their …

An old dog with new tricks: TFEB promotes syncytin expression and cell fusion in the human placenta

SJ Renaud - Genes & Development, 2024 - genesdev.cshlp.org
In the human placenta, cell fusion is crucial for forming the syncytiotrophoblast, a
multinucleated giant cell essential for maintaining pregnancy and ensuring fetal health. The …

Autophagy in reproduction and pregnancy-associated diseases

A Singh, ML Perez, O Kirsanov, E Padilla-Banks… - iScience, 2024 - cell.com
As advantageous as sexual reproduction is during progeny generation, it is also an
expensive and treacherous reproductive strategy. The viviparous eukaryote has evolved to …