Beyond neutralization: Fc-dependent antibody effector functions in SARS-CoV-2 infection
Neutralizing antibodies are known to have a crucial role in protecting against SARS-CoV-2
infection and have been suggested to be a useful correlate of protection for vaccine clinical …
infection and have been suggested to be a useful correlate of protection for vaccine clinical …
Defining the risk of SARS-CoV-2 variants on immune protection
The global emergence of many severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) variants jeopardizes the protective antiviral immunity induced after infection or …
CoV-2) variants jeopardizes the protective antiviral immunity induced after infection or …
Bivalent SARS-CoV-2 mRNA vaccines increase breadth of neutralization and protect against the BA. 5 Omicron variant in mice
SM Scheaffer, D Lee, B Whitener, B Ying, K Wu… - Nature medicine, 2023 - nature.com
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
in the Omicron lineage has resulted in diminished Coronavirus Disease 2019 (COVID-19) …
in the Omicron lineage has resulted in diminished Coronavirus Disease 2019 (COVID-19) …
Population immunity and Covid-19 severity with Omicron variant in South Africa
Abstract Background The B. 1.1. 529 (omicron) variant of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) was first identified on November 25, 2021, in Gauteng …
coronavirus 2 (SARS-CoV-2) was first identified on November 25, 2021, in Gauteng …
mRNA-1273 and BNT162b2 COVID-19 vaccines elicit antibodies with differences in Fc-mediated effector functions
P Kaplonek, D Cizmeci, S Fischinger… - Science translational …, 2022 - science.org
The successful development of several coronavirus disease 2019 (COVID-19) vaccines has
substantially reduced morbidity and mortality in regions of the world where the vaccines …
substantially reduced morbidity and mortality in regions of the world where the vaccines …
Comparison of the immunogenicity of BNT162b2 and CoronaVac COVID‐19 vaccines in Hong Kong
CKP Mok, CA Cohen, SMS Cheng, C Chen… - …, 2022 - Wiley Online Library
Background and objective Few head‐to‐head evaluations of immune responses to different
vaccines have been reported. Methods Surrogate virus neutralization test (sVNT) antibody …
vaccines have been reported. Methods Surrogate virus neutralization test (sVNT) antibody …
Omicron variant Spike-specific antibody binding and Fc activity are preserved in recipients of mRNA or inactivated COVID-19 vaccines
YC Bartsch, X Tong, J Kang, MJ Avendaño… - Science translational …, 2022 - science.org
The Omicron variant of SARS-CoV-2 has been shown to evade neutralizing antibodies
elicited by vaccination or infection. Despite the global spread of the Omicron variant, even …
elicited by vaccination or infection. Despite the global spread of the Omicron variant, even …
An mpox virus mRNA-lipid nanoparticle vaccine confers protection against lethal orthopoxviral challenge
AW Freyn, C Atyeo, PL Earl, JL Americo… - Science translational …, 2023 - science.org
Mpox virus (MPXV) caused a global outbreak in 2022. Although smallpox vaccines were
rapidly deployed to curb spread and disease among those at highest risk, breakthrough …
rapidly deployed to curb spread and disease among those at highest risk, breakthrough …
Immune correlates analysis of the PREVENT-19 COVID-19 vaccine efficacy clinical trial
In the PREVENT-19 phase 3 trial of the NVX-CoV2373 vaccine (NCT04611802), anti-spike
binding IgG concentration (spike IgG), anti-RBD binding IgG concentration (RBD IgG), and …
binding IgG concentration (spike IgG), anti-RBD binding IgG concentration (RBD IgG), and …
XBB. 1.5 spike protein COVID-19 vaccine induces broadly neutralizing and cellular immune responses against EG. 5.1 and emerging XBB variants
N Patel, JF Trost, M Guebre-Xabier, H Zhou… - Scientific Reports, 2023 - nature.com
Abstract Monovalent SARS-CoV-2 Prototype (Wuhan-Hu-1) and bivalent (Prototype+ BA.
4/5) COVID-19 vaccines have demonstrated a waning of vaccine-mediated immunity …
4/5) COVID-19 vaccines have demonstrated a waning of vaccine-mediated immunity …