Assessing the potential of NS2B/NS3 protease inhibitors biomarker in curbing dengue virus infections: In silico vs. In vitro approach
H Norshidah, CH Leow, KE Ezleen… - Frontiers in cellular …, 2023 - frontiersin.org
An increase in the occurrence of viral infectious diseases is a global concern for human
health. According to a WHO report, dengue virus (DENV) is one of the most common viral …
health. According to a WHO report, dengue virus (DENV) is one of the most common viral …
Synthesis, antiproliferative activity and molecular docking studies of 1, 3, 5-triaryl pyrazole compound as estrogen α receptor inhibitor targeting MCF-7 cells line
This research has been successfully synthesized three compounds of 1, 3, 5-triaryl pyrazole
derivatives by two steps reaction. Firstly, pyrazoline (4a-c) compound was obtained by one …
derivatives by two steps reaction. Firstly, pyrazoline (4a-c) compound was obtained by one …
(E)-5-Benzyl-7-(3,4-dimethoxybenzylidene)-3-(3,4-dimethoxyphenyl)-2-phenyl-3,3a,4,5,6,7-hexahydro-2H-pyrazolo[4,3c] Pyridine
A new pyrazolo-pyridine analogue (title compound) was synthesized in two steps. The first
stage was synthesis of monoketone curcumin analogue through Claisen–Schmidt reaction …
stage was synthesis of monoketone curcumin analogue through Claisen–Schmidt reaction …
Synthesis of 4-(5-(2, 3-dimenthoxyphenyl)-3-(4-methoxyphenyl)-4, 5-dihydro-1H-pyrazol-1-y1) benzenesulfonamide as a promosing tyrosinase inhibitor candidate
R Rahayu, N Herfindo, N Oscifiani… - Jurnal Riset …, 2022 - jrk.fmipa.unand.ac.id
In this study, titled compound 5 has been successfully synthesized with 93% yield. The
pyrazoline compound was obtained from the cyclocondensation reaction of 4 …
pyrazoline compound was obtained from the cyclocondensation reaction of 4 …
[PDF][PDF] SINTESIS DAN STUDI MOLECULAR DOCKING SENYAWA PIRAZOLO-PIRIDIN TERSUBSTITUSI METOKSI TURUNAN KURKUMIN MONOKARBONIL …
Scaffold pirazol maupun piazolo-piridin telah dilaporkan memiliki potensi aktivitas biologis
yang menarik dan terdapat pada berbagai struktur senyawa obat yang telah disetujui oleh …
yang menarik dan terdapat pada berbagai struktur senyawa obat yang telah disetujui oleh …
(E)-4-(3-(3-(4-Methoxyphenyl)acryloyl)phenoxy)butyl 2-Hydroxybenzoate
A new hybrid compound of chalcone-salicylate (title compound) has been successfully
synthesized using a linker mode approach under reflux condition. The structure of the title …
synthesized using a linker mode approach under reflux condition. The structure of the title …
Synthesis and Evaluation of Some Sulfonamide-Substituted of 1, 3, 5-Triphenyl Pyrazoline Derivatives as Tyrosinase Enzyme Inhibitors
N Herfindo, N Frimayanti - Molekul, 2023 - jos.unsoed.ac.id
Pyrazoline is well-known as heterocycles compound that can exhibit many biological effects.
In this work, we synthesized a series of sulfonamide-substituted 1, 3, 5-triphenyl pyrazoline …
In this work, we synthesized a series of sulfonamide-substituted 1, 3, 5-triphenyl pyrazoline …
5-(4-Fluorophenyl)-3-(naphthalen-1-yl)-1-phenyl-1H-pyrazole
A new fluorinated pyrazole, 5-(4-fluorophenyl)-3-(naphthalen-1-yl)-1-phenyl-1 H-pyrazole
was successfully synthesized via a two-step reaction. Firstly, the synthesis of pyrazoline was …
was successfully synthesized via a two-step reaction. Firstly, the synthesis of pyrazoline was …
Assessing the potential of NS2B/NS3 protease inhibitors biomarker in curbing dengue virus infections: In silico vs. In vitro approach
N Harun, LC Herng, EE Kamarulzaman, HA Wahab… - 2023 - ir.unikl.edu.my
An increase in the occurrence of viral infectious diseases is a global concern for human
health. According to a WHO report, dengue virus (DENV) is one of the most common viral …
health. According to a WHO report, dengue virus (DENV) is one of the most common viral …
Microwave-assisted synthesis of a fluorinated pyrazoline, in silico study and in vitro cytotoxic evaluation against HeLa cell line
Pyrazoline analogues have been reported with some significant biological activities, such as
anticancer, antidiabetic and antimalarial. In this work, a fluorinated pyrazoline analogue, 5 …
anticancer, antidiabetic and antimalarial. In this work, a fluorinated pyrazoline analogue, 5 …