Relationship between oxidative stress, ER stress, and inflammation in type 2 diabetes: the battle continues
E Burgos-Morón, Z Abad-Jiménez… - Journal of clinical …, 2019 - mdpi.com
Type 2 diabetes (T2D) is a metabolic disorder characterized by hyperglycemia and insulin
resistance in which oxidative stress is thought to be a primary cause. Considering that …
resistance in which oxidative stress is thought to be a primary cause. Considering that …
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
L Galluzzi, I Vitale, SA Aaronson, JM Abrams… - Cell Death & …, 2018 - nature.com
Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated
guidelines for the definition and interpretation of cell death from morphological, biochemical …
guidelines for the definition and interpretation of cell death from morphological, biochemical …
Capture at the ER-mitochondrial contacts licenses IP3 receptors to stimulate local Ca2+ transfer and oxidative metabolism
Endoplasmic reticulum-mitochondria contacts (ERMCs) are restructured in response to
changes in cell state. While this restructuring has been implicated as a cause or …
changes in cell state. While this restructuring has been implicated as a cause or …
Insulin resistance and diabetes mellitus in Alzheimer's disease
Type 2 diabetes mellitus is a progressive disease that is characterized by the appearance of
insulin resistance. The term insulin resistance is very wide and could affect different proteins …
insulin resistance. The term insulin resistance is very wide and could affect different proteins …
Phospholipids and cholesterol: Inducers of cancer multidrug resistance and therapeutic targets
J Kopecka, P Trouillas, AČ Gašparović, E Gazzano… - Drug resistance …, 2020 - Elsevier
Lipids, phospholipids and cholesterol in particular, are the predominant components of the
plasma membrane, wherein multidrug efflux transporters of the ATP-binding cassette (ABC) …
plasma membrane, wherein multidrug efflux transporters of the ATP-binding cassette (ABC) …
Autophagy regulates fatty acid availability for oxidative phosphorylation through mitochondria-endoplasmic reticulum contact sites
Autophagy has been associated with oncogenesis with one of its emerging key functions
being its contribution to the metabolism of tumors. Therefore, deciphering the mechanisms of …
being its contribution to the metabolism of tumors. Therefore, deciphering the mechanisms of …
Mitophagy in cancer: a tale of adaptation
M Vara-Perez, B Felipe-Abrio, P Agostinis - Cells, 2019 - mdpi.com
In the past years, we have learnt that tumors co-evolve with their microenvironment, and that
the active interaction between cancer cells and stromal cells plays a pivotal role in cancer …
the active interaction between cancer cells and stromal cells plays a pivotal role in cancer …
Crosstalks between inflammasome and autophagy in cancer
Both inflammasomes and autophagy have important roles in the intracellular homeostasis,
inflammation, and pathology; the dysregulation of these processes is often associated with …
inflammation, and pathology; the dysregulation of these processes is often associated with …
ER-mitochondria contact sites; a multifaceted factory for Ca2+ signaling and lipid transport
ML Sassano, B Felipe-Abrio… - Frontiers in Cell and …, 2022 - frontiersin.org
Membrane contact sites (MCS) between organelles of eukaryotic cells provide structural
integrity and promote organelle homeostasis by facilitating intracellular signaling, exchange …
integrity and promote organelle homeostasis by facilitating intracellular signaling, exchange …
FUNDC1-dependent mitochondria-associated endoplasmic reticulum membranes are involved in angiogenesis and neoangiogenesis
Abstract FUN14 domain-containing protein 1 (FUNDC1) is an integral mitochondrial outer-
membrane protein, and mediates the formation of mitochondria-associated endoplasmic …
membrane protein, and mediates the formation of mitochondria-associated endoplasmic …