The majority of studies on microRNA-200 family members (miR-200s) in human cancers are
based on the premise that miR-200s maintain epithelial cell integrity by suppressing …

Despite noteworthy progress made in the management and treatment of HIV/AIDS-related
disease, including the introduction of the now almost ubiquitous HAART, there remains …

Over many years, research on HIV/AIDS has advanced with the introduction of HAART.
Despite these advancements, significant gaps remain with respect to aspects in HIV life …

Background Eya1 is a critical regulator of nephron progenitor cell specification and interacts
with Six2 to promote NPC self-renewal. Haploinsufficiency of these genes causes kidney …

MicroRNAs (miRNAs) are short, single-stranded, noncoding RNAs that modulate many key
biological processes by simultaneously suppressing multiple target genes. Among them …

Podocyte dysfunction results in glomerular diseases accounted for 90% of end‐stage kidney
disease. The evolutionarily conserved Notch signalling makes a crucial contribution in …

Neuronal apoptosis is a central hallmark of cerebral ischemia, which is serious threats to
human health. Notch1 signaling pathway and three members of miR-200 family, miR-429 …

Membranous nephropathy (MN) is a leading cause of nephrotic syndrome in adults and is
associated with high rates of end-stage renal disease. Early detection and precise …

Viperin (also known as radical SAM domain–containing 2 (RSAD2)) is an interferon-
inducible and evolutionary conserved protein that participates in the cell's innate immune …

The mammalian eye lens expresses a high concentration of crystallins (α, β and γ-
crystallins) to maintain the refractive index essential for lens transparency. Crystallins are …