Targeted drug delivery strategies for precision medicines
Progress in the field of precision medicine has changed the landscape of cancer therapy.
Precision medicine is propelled by technologies that enable molecular profiling, genomic …
Precision medicine is propelled by technologies that enable molecular profiling, genomic …
Recent advances in tumor targeting via EPR effect for cancer treatment
Cancer causes the second-highest rate of death world-wide. A major shortcoming inherent
in most of anticancer drugs is their lack of tumor selectivity. Nanodrugs for cancer therapy …
in most of anticancer drugs is their lack of tumor selectivity. Nanodrugs for cancer therapy …
The use of alternative strategies for enhanced nanoparticle delivery to solid tumors
M Izci, C Maksoudian, BB Manshian… - Chemical …, 2021 - ACS Publications
Nanomaterial (NM) delivery to solid tumors has been the focus of intense research for over a
decade. Classically, scientists have tried to improve NM delivery by employing passive or …
decade. Classically, scientists have tried to improve NM delivery by employing passive or …
Smart cancer nanomedicine
Nanomedicines are extensively employed in cancer therapy. We here propose four strategic
directions to improve nanomedicine translation and exploitation.(1) Patient stratification has …
directions to improve nanomedicine translation and exploitation.(1) Patient stratification has …
Strategies to enhance drug delivery to solid tumors by harnessing the EPR effects and alternative targeting mechanisms
Abstract The Enhanced Permeability and Retention (EPR) effect has been recognized as the
central paradigm in tumor-targeted delivery in the last decades. In the wake of this concept …
central paradigm in tumor-targeted delivery in the last decades. In the wake of this concept …
Nanoprobe-based molecular imaging for tumor stratification
X Ma, M Mao, J He, C Liang, HY Xie - Chemical Society Reviews, 2023 - pubs.rsc.org
The responses of patients to tumor therapies vary due to tumor heterogeneity. Tumor
stratification has been attracting increasing attention for accurately distinguishing between …
stratification has been attracting increasing attention for accurately distinguishing between …
Tumor targeting via EPR: Strategies to enhance patient responses
The tumor accumulation of nanomedicines relies on the enhanced permeability and
retention (EPR) effect. In the last 5–10 years, it has been increasingly recognized that there …
retention (EPR) effect. In the last 5–10 years, it has been increasingly recognized that there …
Radiolabelling of nanomaterials for medical imaging and therapy
Nanomaterials offer unique physical, chemical and biological properties of interest for
medical imaging and therapy. Over the last two decades, there has been an increasing effort …
medical imaging and therapy. Over the last two decades, there has been an increasing effort …
Marriage of black phosphorus and Cu2+ as effective photothermal agents for PET-guided combination cancer therapy
K Hu, L Xie, Y Zhang, M Hanyu, Z Yang… - Nature …, 2020 - nature.com
The use of photothermal agents (PTAs) in cancer photothermal therapy (PTT) has shown
promising results in clinical studies. The rapid degradation of PTAs may address safety …
promising results in clinical studies. The rapid degradation of PTAs may address safety …
Rethinking cancer nanotheranostics
Advances in nanoparticle synthesis and engineering have produced nanoscale agents
affording both therapeutic and diagnostic functions that are often referred to by the …
affording both therapeutic and diagnostic functions that are often referred to by the …