For over 150 years, bronchoscopy, especially flexible bronchoscopy, has been a mainstay
for airway inspection, the diagnosis of airway lesions, therapeutic aspiration of airway …

Introduction The effects of nocturnal noninvasive positive pressure ventilation (NIPPV) in
patients with stable chronic obstructive pulmonary disease (COPD) remain controversial …

Importance Preliminary clinical trials have demonstrated that endobronchial coils compress
emphysematous lung tissue and may improve lung function, exercise tolerance, and …

Importance Therapeutic options for severe emphysema are limited. Lung volume reduction
using nitinol coils is a bronchoscopic intervention inducing regional parenchymal volume …

Background Few treatment options exist for patients with severe emphysema. We assessed
the clinical benefits and safety of lung volume reduction coils (LVRCs) for the treatment of …

The era of bronchoscopy began with Gustav Killian in 1876 when he removed a pork bone
from a farmer's airway, using an esophagoscope. Prompted by this accomplishment …

Advanced emphysema is a lung disease in which alveolar capillary units are destroyed and
supporting tissue is lost. The combined effect of reduced gas exchange and changes in …

Background The lung volume reduction (LVR) coil is a minimally invasive bronchoscopic
nitinol device designed to reduce hyperinflation and improve elastic recoil in severe …

Uncontrolled pilot studies demonstrated promising results of endoscopic lung volume
reduction using emphysematous lung sealant (ELS) in patients with advanced, upper lobe …

COPD is a highly prevalent, chronic and irreversible obstructive airway disease without
curative treatment. Standard therapeutic strategies, both non-pharmacological and …