[HTML][HTML] Clinical implications of the intrinsic molecular subtypes in hormone receptor-positive and HER2-negative metastatic breast cancer

C Falato, F Schettini, T Pascual… - Cancer Treatment …, 2023 - Elsevier
Traditionally, the classification of breast cancer relies on the expression of
immunohistochemical (IHC) biomarkers readily available in clinical practice. Using highly …

Clinical utility of genomic signatures for the management of early and metastatic triple-negative breast cancer

G Castellano, F Giugliano, G Curigliano… - Current Opinion in …, 2023 - journals.lww.com
The findings discussed in this review have significant implications for clinical practice and
research in TNBC. The identification of distinct molecular subtypes through gene expression …

Efficacy of front-line treatment for hormone receptor-positive HER2-negative metastatic breast cancer with germline BRCA1/2 mutation

JS Frenel, A Lusque, S Delaloge, JM Ferrero… - British Journal of …, 2023 - nature.com
Background Efficacy of endocrine therapy in HR+/HER2− metastatic breast cancer could
differ depending on the presence of BRCA1/2 germline mutation. Methods The ESME …

Update Breast Cancer 2022 Part 6–Advanced-Stage Breast Cancer

D Lüftner, MP Lux, TN Fehm, M Welslau… - Geburtshilfe und …, 2023 - thieme-connect.com
Die in den letzten Jahren begonnenen großen Studienprogramme zu den CDK4/6-
Inhibitoren, den zielgerichteten Therapien und den Antikörper-Medikament-Konjugaten …

[HTML][HTML] Liquid biopsy to tailor the treatment of advanced hormone receptor-positive breast cancer in the era of novel endocrine agents and CDK4/6-inhibitors

E Seguí, F Schettini - Annals of Translational Medicine, 2024 - ncbi.nlm.nih.gov
Genomics and Targeted Therapies in Solid Tumors, August Pi i Sunyer Biomedical
Research Institute (FRCB-IDIBAPS), Barcelona, Spain; 4Faculty of Medicine and Health …

CDK4/6 Inhibition–Therapy Sequences and the Quest to Find the Best Biomarkers–an Overview of Current Programs

A Schneeweiss, SY Brucker, H Huebner… - Geburtshilfe und …, 2024 - thieme-connect.com
Für Patientinnen wie auch Patienten mit hormonrezeptorpositivem (HRpos)/Human
epidermal growth factor receptor 2-negativem (HER2neg) Mammakarzinom wurden in den …

The Challenges of Lobular Carcinomas from a Surgeon's Point of View

MLH Riis - Clinical Breast Cancer, 2024 - Elsevier
Invasive lobular breast cancer (ILC) presents unique challenges and considerations in the
realm of surgical management. Characterized by its distinct histological features, including …

[HTML][HTML] Update Breast Cancer 2023 Part 1–Early Stage Breast Cancer

AD Hartkopf, TN Fehm, M Welslau… - Geburtshilfe und …, 2023 - thieme-connect.com
Mit den Zulassungen von Abemaciclib (monarchE-Studie) und Olaparib (OlympiA-Studie) in
der adjuvanten Therapiesituation haben sich die Therapiestandards bei der Behandlung …

Update Mammakarzinom 2022 Teil 6–Brustkrebs in fortgeschrittenen Krankheitsstadien

D Lüftner, MP Lux, TN Fehm, M Welslau… - Senologie-Zeitschrift …, 2023 - thieme-connect.com
Die in den letzten Jahren begonnenen großen Studienprogramme zu den CDK4/6-
Inhibitoren, den zielgerichteten Therapien und den Antikörper-Medikament-Konjugaten …

[HTML][HTML] OS Advances Gather Steam in Breast Cancer

AT Shaffer - letlifehappen.com
The treatment of patients with breast cancer is making noteworthy strides in several clinical
settings, with recent trial results showing overall survival (OS) improvements for advanced …