In human pathophysiology, the clash between microbial infection and host immunity
contributes to multiple diseases. Cystic fibrosis (CF) is a classical example of this …

Pseudomonas aeruginosa is a Gram-negative bacterium belonging to the γ-proteobacteria.
Like other members of the Pseudomonas genus, it is known for its metabolic versatility and …

Many bacterial species have been found to exist in a viable but non-culturable (VBNC) state
since its discovery in 1982. VBNC cells are characterized by a loss of culturability on routine …

Reactive oxygen species (ROS) are attractive weapons in both antibiotic-mediated killing
and host-mediated killing. However, the involvement of ROS in antibiotic-mediated killing …

Secondary metabolites profoundly affect microbial physiology, metabolism and stress
responses. Increasing evidence suggests that these molecules can modulate microbial …

Microbes rely upon iron as a cofactor for many enzymes in their central metabolic processes.
The reactive oxygen species (ROS) superoxide and hydrogen peroxide react rapidly with …

Pseudomonas aeruginosa is a metabolically versatile bacterium that is found in a wide
range of biotic and abiotic habitats. It is a major human opportunistic pathogen causing …

Gene expression occurs in two essential steps: transcription and translation. In bacteria, the
two processes are tightly coupled in time and space, and highly regulated. Tight regulation …

Biofilms constitute the predominant microbial style of life in natural and engineered
ecosystems. Facing harsh environmental conditions, microorganisms accumulate reactive …

Members of the Pseudomonas genus produce diverse secondary metabolites affecting other
bacteria, fungi or predating nematodes and protozoa but are also equipped with the capacity …