Blood self-sampling devices: innovation, interpretation and implementation in total lab automation

DCW Poland, CM Cobbaert - Clinical Chemistry and Laboratory …, 2025 - degruyter.com
The introduction of the vacuum tube in 1949 revolutionized blood collection, significantly
improving sample quality and patient comfort. Over the past 75 years, laboratory diagnostics …

Recent Contributions of Mass Spectrometry-Based “Omics” in the Studies of Breast Cancer

S Banerjee, M Hatimuria, K Sarkar, J Das… - Chemical Research …, 2023 - ACS Publications
Breast cancer (BC) is one of the most heterogeneous groups of cancer. As every biotype of
BC is unique and presents a particular “omic” signature, they are increasingly characterized …

[HTML][HTML] Simultaneous detection of myostatin-targeting monoclonal antibodies in dried blood spots and plasma using liquid chromatography-tandem mass …

HJ Lee, J Hwang, Y Seo, G Lee, HJ Lee… - Journal of Pharmaceutical …, 2025 - Elsevier
Transforming growth factor-β superfamily members, such as myostatin, growth/differentiation
factor 11, and activin A, negatively regulate skeletal muscle mass. Inhibitors targeting these …

[HTML][HTML] Quantification of Letrozole, Palbociclib, Ribociclib, Abemaciclib, and Metabolites in Volumetric Dried Blood Spots: Development and Validation of an LC-MS …

E Cecchin, M Orleni, S Gagno… - International …, 2024 - pmc.ncbi.nlm.nih.gov
Therapeutic drug monitoring (TDM) may be beneficial for cyclin-dependent kinase 4/6
inhibitors (CDK4/6is), such as palbociclib, ribociclib, and abemaciclib, due to established …

Targeted and untargeted metabolomics and lipidomics in dried blood microsampling: Recent applications and perspectives

P Couacault, D Avella… - Analytical Science …, 2024 - Wiley Online Library
Blood microsampling (BµS) offers an alternative to conventional methods that use plasma or
serum for profiling human health, being minimally invasive and cost effective, especially …

Development of a simple high-performance liquid chromatography-ultraviolet detection method for olaparib in patients with ovarian cancer

T Yasu, R Nishijima, R Ikuta, M Shirota… - Drug Discoveries & …, 2023 - jstage.jst.go.jp
Olaparib is a small-molecule inhibitor of poly (ADP)-ribose polymerase (PARP) used as
maintenance therapy for recurrent ovarian cancer and newly diagnosed advanced ovarian …

BIOANALYTICAL METHOD VALIDATION FOR THERAPEUTIC DRUG MONITORING OF OLAPARIB IN PATIENTS WITH OVARIAN CANCER.

K LEWANDOWSKI, A KARBOWNIK… - Acta Poloniae …, 2024 - search.ebscohost.com
Olaparib, an oral poly-ADP ribose polymerase (PARP) inhibitor, is a relatively new
anticancer drug. It is essential to find TDM-guided dosage for better safety and tolerability …