The Flaviviridae virus family consists of the genera Hepacivirus, Pestivirus, and Flavivirus, with approximately 70 viral types that use arthropods as vectors. Among these diseases …
The present-day world is severely suffering from the recently emerged SARS-CoV-2. The lack of prescribed drugs for the deadly virus has stressed the likely need to identify novel …
S Yuan, CCY Chan, KKH Chik, JOL Tsang, R Liang… - Viruses, 2020 - mdpi.com
The ongoing Coronavirus Disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) signals an urgent need for an expansion …
The recent outbreak of the coronavirus disease 2019 (COVID‐19) caused by SARS‐CoV‐2 (severe acute respiratory syndrome coronavirus 2) in the last few months raised global …
SN Bolz, MF Adasme, M Schroeder - Journal of Chemical …, 2021 - ACS Publications
Pan-assay interference compounds (PAINS) are promiscuous compound classes that produce false positive hits in high-throughput screenings. Yet, the mechanisms of PAINS …
DAF Nunes, FRS Santos… - Journal of Medical …, 2022 - Wiley Online Library
Zika virus (ZIKV) infections are associated with severe neurological complications and are a global public health concern. There are no approved vaccines or antiviral drugs to inhibit …
P Godara, B Naik, R Meghwal, R Ojha, V Srivastava… - Life Sciences, 2022 - Elsevier
Aims Malaria deaths occur primarily due to complicated malaria associated with the sequestration of Plasmodium falciparum-infected erythrocyte (Pf IE) in the capillary …
The emergence of drug-resistance-inducing mutations in Hepatitis C virus (HCV) coupled with genotypic heterogeneity has made targeting NS3/4A serine protease difficult. In this …
Y Zhang, H Zhang, K Gao - Organic Letters, 2021 - ACS Publications
We report herein that a borane–trimethylamine complex worked as an efficient reducing agent for the selective methylation and formylation of amines with 1 atm CO2 under metal …