The traumatic bone: trauma-induced heterotopic ossification

D Dey, BM Wheatley, D Cholok, S Agarwal, BY Paul… - Translational …, 2017 - Elsevier
Heterotopic ossification (HO) is a common occurrence after multiple forms of extensive
trauma. These include arthroplasties, traumatic brain and spinal cord injuries, extensive …

Pathogenesis of acquired heterotopic ossification: risk factors, cellular mechanisms, and therapeutic implications

G Cao, S Zhang, Y Wang, S Quan, C Yue, J Yao… - Bone, 2023 - Elsevier
Heterotopic ossification (HO), including hereditary and acquired HO, is the formation of
extraskeletal bone in skeletal muscle and surrounding soft tissues. Acquired HO is often …

Neurological heterotopic ossification following spinal cord injury is triggered by macrophage‐mediated inflammation in muscle

F Genêt, I Kulina, C Vaquette, F Torossian… - The Journal of …, 2015 - Wiley Online Library
Neurological heterotopic ossification (NHO) is the abnormal formation of bone in soft tissues
as a consequence of spinal cord or traumatic brain injury. NHO causes pain, ankyloses …

[图书][B] Traumatic brain injury: Methods for clinical and forensic neuropsychiatric assessment

C Catanese - 2007 - taylorfrancis.com
Since the original publication of Traumatic Brain Injury: Methods for Clinical & Forensic
Neuropsychiatric Assessment, enhanced clinical findings concerning traumatic brain injury …

Neurological heterotopic ossification: novel mechanisms, prognostic biomarkers and prophylactic therapies

KR Wong, R Mychasiuk, TJ O'Brien, SR Shultz… - Bone Research, 2020 - nature.com
Neurological heterotopic ossification (NHO) is a debilitating condition where bone forms in
soft tissue, such as muscle surrounding the hip and knee, following an injury to the brain or …

Rehabilitation after traumatic brain injury

MA Iaccarino, S Bhatnagar, R Zafonte - Handbook of clinical neurology, 2015 - Elsevier
Traumatic brain injury (TBI) is a growing problem in the US, with significant morbidity and
economic implications. This diagnosis spans a wide breath of injuries from concussion to …

Post‐traumatic heterotopic ossification: an old problem in need of new solutions

N Eisenstein, S Stapley, L Grover - Journal of Orthopaedic …, 2018 - Wiley Online Library
Heterotopic ossification (HO) is the formation of pathological bone in ectopic sites and it can
have serious consequences for functional outcomes. For many years, its main clinical …

Inhibition of JAK1/2 tyrosine kinases reduces neurogenic heterotopic ossification after spinal cord injury

KA Alexander, HW Tseng, W Fleming, B Jose… - Frontiers in …, 2019 - frontiersin.org
Neurogenic heterotopic ossifications (NHO) are very incapacitating complications of
traumatic brain and spinal cord injuries (SCI) which manifest as abnormal formation of bone …

When the nervous system turns skeletal muscles into bones: how to solve the conundrum of neurogenic heterotopic ossification

KA Alexander, HW Tseng, M Salga, F Genêt… - Current osteoporosis …, 2020 - Springer
Abstract Purpose of Review Neurogenic heterotopic ossification (NHO) is the abnormal
formation of extra-skeletal bones in periarticular muscles after damage to the central …

Subacute complications during recovery from severe traumatic brain injury: frequency and associations with outcome

AK Godbolt, M Stenberg, J Jakobsson, K Sorjonen… - BMJ open, 2015 - bmjopen.bmj.com
Background Medical complications after severe traumatic brain injury (S-TBI) may delay or
prevent transfer to rehabilitation units and impact on long-term outcome. Objective Mapping …