Leptin as a key regulator of the adipose organ

C Picó, M Palou, CA Pomar, AM Rodríguez… - Reviews in Endocrine …, 2022 - Springer
Leptin is a hormone primarily produced by the adipose tissue in proportion to the size of fat
stores, with a primary function in the control of lipid reserves. Besides adipose tissue, leptin …

Lactation as a programming window for metabolic syndrome

C Picó, F Reis, C Egas, P Mathias… - European Journal of …, 2021 - Wiley Online Library
The concept of developmental origins of health and disease (DOHaD) was initially
supported by the low birth weight and higher risk of developing cardiovascular disease in …

Leptin as a breast milk component for the prevention of obesity

M Palou, C Picó, A Palou - Nutrition reviews, 2018 - academic.oup.com
Leptin ingested as a component of breast milk is increasingly recognized to play a role in the
postnatal programming of a healthy phenotype in adulthood. Besides its primary function in …

Influence of maternal metabolic status and diet during the perinatal period on the metabolic programming by leptin ingested during the suckling period in rats

P Castillo, CA Pomar, A Palou, M Palou, C Picó - Nutrients, 2023 - mdpi.com
We aimed to analyze the long-term metabolic effects of leptin supplementation at
physiological doses during suckling in the offspring of diet-induced obese rats, together with …

'Optimising'breastfeeding: what can we learn from evolutionary, comparative and anthropological aspects of lactation?

MS Fewtrell, NH Mohd Shukri, JCK Wells - BMC medicine, 2020 - Springer
Background Promoting breastfeeding is an important public health intervention, with benefits
for infants and mothers. Even modest increases in prevalence and duration may yield …

[HTML][HTML] Implementation of a healthy diet to lactating rats attenuates the early detrimental programming effects in the offspring born to obese dams. Putative …

CA Pomar, P Castillo, M Palou, A Palou… - The Journal of nutritional …, 2022 - Elsevier
Lactation is a critical period of development and alterations in milk composition due to
maternal diet or status may affect infant growth. We aimed to evaluate in rats whether …

Centering human milk composition as normal human biological variation

EA Quinn - American Journal of Human Biology, 2021 - Wiley Online Library
Objectives Human biological variation in the phenotype is the cornerstone of modern human
biology, evolutionary anthropology, and related studies of human evolution. Minimal …

In rats fed high-energy diets, taste, rather than fat content, is the key factor increasing food intake: a comparison of a cafeteria and a lipid-supplemented standard diet

L Oliva, T Aranda, G Caviola, A Fernández-Bernal… - PeerJ, 2017 - peerj.com
Background Food selection and ingestion both in humans and rodents, often is a critical
factor in determining excess energy intake and its related disorders. Methods Two different …

Maternal obesity during lactation may protect offspring from high fat diet-induced metabolic dysfunction

J Monks, DJ Orlicky, AL Stefanski, AE Libby… - Nutrition & …, 2018 - nature.com
Abstract Background/Objectives The current obesity epidemic has spurred exploration of the
developmental origin of adult heath and disease. A mother's dietary choices and health can …

Combination of capsaicin and hesperidin reduces the effectiveness of each compound to decrease the adipocyte size and to induce browning features in adipose …

A Mosqueda-Solis, J Sánchez, MP Portillo… - Journal of agricultural …, 2018 - ACS Publications
We explored the potential of hesperidin and capsaicin, separately and in combination, to
induce white adipose tissue (WAT) browning and to help body weight management in …