The role of galectin-3 in heart failure—the diagnostic, prognostic and therapeutic potential—where do we stand?

B Zaborska, M Sikora-Frąc, K Smarż… - International Journal of …, 2023 - mdpi.com
Heart failure (HF) is a clinical syndrome with high morbidity and mortality, and its prevalence
is rapidly increasing. Galectin-3 (Gal-3) is an important factor in the pathophysiology of HF …

Macrophage-based therapeutic approaches for cardiovascular diseases

M Sansonetti, B Al Soodi, T Thum, M Jung - Basic Research in Cardiology, 2024 - Springer
Despite the advances in treatment options, cardiovascular disease (CVDs) remains the
leading cause of death over the world. Chronic inflammatory response and irreversible …

From classic to modern prognostic biomarkers in patients with acute myocardial infarction

C Stătescu, L Anghel, BS Tudurachi, A Leonte… - International Journal of …, 2022 - mdpi.com
Despite all the important advances in its diagnosis and treatment, acute myocardial
infarction (AMI) is still one of the most prominent causes of morbidity and mortality …

Personalized management of myocarditis and inflammatory cardiomyopathy in clinical practice

A Tymińska, K Ozierański, A Skwarek… - Journal of Personalized …, 2022 - mdpi.com
Myocarditis is an inflammatory heart disease induced by infectious and non-infectious
causes frequently triggering immune-mediated pathologic mechanisms leading to …

The association between soluble suppression of tumorigenicity-2 and long-term prognosis in patients with coronary artery disease: A meta-analysis

N Liu, T Hang, X Gao, W Yang, W Kong, Q Lou… - PLoS one, 2020 - journals.plos.org
Objective Findings regarding the prognostic value of soluble suppression of tumorigenecity-
2 (sST2) in patients with coronary artery disease (CAD) remain inconsistent. Therefore, we …

Emerging biomarkers for predicting clinical outcomes in patients with heart disease

K Pál, IB Mănescu, S Lupu, M Dobreanu - Life, 2023 - mdpi.com
Cardiovascular disease is most frequently caused by the development and progression of
atherosclerosis. When coronary arteries are afflicted, and the stenoses caused by …

Association of soluble suppression of tumorigenicity with no-reflow phenomenon and long-term prognosis in patients with non-ST-segment elevation acute coronary …

Q Zhang, M Hu, S Ma - Journal of atherosclerosis and thrombosis, 2021 - jstage.jst.go.jp
Aims: Soluble suppression of tumorigenicity 2 (sST2) was validated to independently predict
prognosis for heart failure (HF) and ST-segment elevation myocardial infarction (STEMI). In …

An elevated level of soluble suppression of tumorigenicity 2, but not galectin-3, is associated with the presence of coronary artery disease in hypertensive patients

E Miura-Takahashi, R Tsudome, Y Suematsu… - Hypertension …, 2024 - nature.com
We investigated whether there were associations between coronary artery disease (CAD)
and soluble suppression of tumorigenicity (sST2) and galectin-3 levels at the time of …

The role of galectin-3 in retinal degeneration and other ocular diseases: a potential novel biomarker and therapeutic target

Z Zhou, Z Feng, X Sun, Y Wang, G Dou - International Journal of …, 2023 - mdpi.com
Galectin-3 is the most studied member of the Galectin family, with a large range of mediation
in biological activities such as cell growth, proliferation, apoptosis, differentiation, cell …

Galectin-3 as a Prognostic Biomarker in Patients with First Acute Myocardial Infarction without Heart Failure

RM Vucic, OM Andrejic, D Stokanovic, TJ Stoimenov… - Diagnostics, 2023 - mdpi.com
Background: Galectin-3 (Gal-3) is a biomarker involved in a wide range of diseases
including cardiac remodeling following acute myocardial infarction (AMI). Identification of …