Clinical trials consume the latter half of the 10 to 15 year, 1.5–2.0 billion USD, development
cycle for bringing a single new drug to market. Hence, a failed trial sinks not only the …

The resistive pulse sensing (RPS) method based on the Coulter principle is a powerful
method for particle counting and sizing in electrolyte solutions. With the advancement of …

Abstract Pharma 4.0, a technology ecosystem in drug development analogous to Industry
4.0 in healthcare, is transforming the traditional approach to drug discovery and …

Bioinspired pore sensing for selective detection of flagellated bacteria was investigated. The
Au micropore wall surface was modified with a synthetic peptide designed from toll-like …

The control of biomolecule translocation through nanopores is important in nanopore protein
detection. Improvement in current nanopore molecule control is desired to enhance capture …

Modified tiny hydrogen-terminated diamond structures, known as diamondoids, show a high
efficiency in sensing DNA molecules. These diamond cages, as recently proposed, could …

This paper presents the detection of nanoparticles and microorganisms using a recently
developed side-orifice-based resistive pulse sensor (SO-RPS). By decreasing the channel …

The advent of nanopore-based sensors based on resistive pulse sensing gave rise to a
remarkable breakthrough in the detection and characterization of nanoscale species. Some …

The construction of biosensors for specific, sensitive, and rapid detection of tumor
biomarkers significantly contributes to biomedical research and early cancer diagnosis …

Understanding and controlling electrophoretic motions of nanoscopic objects in fluidic
channels are a central challenge in developing nanopore technology for molecular …