Mechanosensitive membrane proteins: Usual and unusual suspects in mediating mechanotransduction

MB Goodman, ES Haswell, V Vásquez - Journal of General Physiology, 2023 - rupress.org
This Viewpoint, which accompanies a Special Issue focusing on membrane
mechanosensors, discusses unifying and unique features of both established and emerging …

Sonogenetics for Monitoring and Modulating Biomolecular Function by Ultrasound

J Hahmann, A Ishaqat, T Lammers… - Angewandte Chemie …, 2024 - Wiley Online Library
Ultrasound technology, synergistically harnessed with genetic engineering and chemistry
concepts, has started to open the gateway to the remarkable realm of sonogenetics—a …

Activation of mechanosensitive ion channels by ultrasound

YC Chu, J Lim, A Chien, CC Chen, JL Wang - Ultrasound in medicine & …, 2022 - Elsevier
Mechanosensitive channels (MSCs) play an important role in how cells transduce
mechanical stimuli into electrical or chemical signals, which provides an interventional …

Generating multistructured ultrasound via bioinspired metaskin patterning for low‐threshold and contactless control of living organisms

PQ Li, ZL Li, W Zhou, S Wang, L Meng… - Advanced Functional …, 2022 - Wiley Online Library
Metasurfaces of the subwavelength thicknesses provide a distinctive route for acoustic wave
manipulation. Based on the advanced 3D printing, those judiciously designed 2D …

Two pathways are required for ultrasound-evoked behavioral changes in Caenorhabditis elegans

U Magaram, C Weiss, A Vasan, KC Reddy, J Friend… - PloS one, 2022 - journals.plos.org
Ultrasound has been shown to affect the function of both neurons and non-neuronal cells,
but, the underlying molecular machinery has been poorly understood. Here, we show that at …

Genetically encoded mediators for sonogenetics and their applications in neuromodulation

HC Wang, TN Phan, CL Kao, CK Yeh… - Frontiers in Cellular …, 2023 - frontiersin.org
Sonogenetics is an emerging approach that harnesses ultrasound for the manipulation of
genetically modified cells. The great penetrability of ultrasound waves enables the non …

Sonogenetics in the Treatment of Chronic Diseases: A New Method for Cell Regulation

M Zhu, Y Fang, Y Sun, S Li, J Yu, B Xiong… - Advanced …, 2024 - Wiley Online Library
Sonogenetics is an innovative technology that integrates ultrasound with genetic editing to
precisely modulate cellular activities in a non‐invasive manner. This method entails …

[HTML][HTML] Advancing Neuroscience and Therapy: Insights into Genetic and Non-Genetic Neuromodulation Approaches

W Zhi, Y Li, L Wang, X Hu - Cells, 2025 - mdpi.com
Neuromodulation stands as a cutting-edge approach in the fields of neuroscience and
therapeutic intervention typically involving the regulation of neural activity through physical …

Mechanosensitive Ion Channels Piezo1 and Piezo2 in Vivo Mediate Motor Response During Transcranial Focused Ultrasound Stimulation of Rodent Cerebral Motor …

T Xu, Y Zhang, D Li, C Lai, S Wang… - IEEE Transactions on …, 2024 - ieeexplore.ieee.org
Objective: Transcranial focused ultrasound (tFUS) neuromodulation offers a noninvasive,
safe, deep brain stimulation with high precision, presenting potential in understanding …

Selective sub-nucleus ultrasound stimulation induces synaptic potentiation in the mouse hippocampus

W Zhou, P Li, W Meng, SH Zheng… - IEEE Transactions …, 2025 - ieeexplore.ieee.org
Ultrasound neuromodulation enables to elicit long-lasting effect on neural activities and
behavioral responses across species, including humans. However, the potential biophysical …