Coarse-graining methods for computational biology

MG Saunders, GA Voth - Annual review of biophysics, 2013 - annualreviews.org
Connecting the molecular world to biology requires understanding how molecular-scale
dynamics propagate upward in scale to define the function of biological structures. To …

Dissipative self‐assembly driven by the consumption of chemical fuels

S De, R Klajn - Advanced Materials, 2018 - Wiley Online Library
Dissipative self‐assembly leads to structures and materials that exist away from equilibrium
by continuously exchanging energy and materials with the external environment. Although …

Electrostatic co-assembly of nanoparticles with oppositely charged small molecules into static and dynamic superstructures

T Bian, A Gardin, J Gemen, L Houben, C Perego… - Nature …, 2021 - nature.com
Coulombic interactions can be used to assemble charged nanoparticles into higher-order
structures, but the process requires oppositely charged partners that are similarly sized. The …

Principles of self-organization and load adaptation by the actin cytoskeleton during clathrin-mediated endocytosis

M Akamatsu, R Vasan, D Serwas, MA Ferrin… - Elife, 2020 - elifesciences.org
Force generation by actin assembly shapes cellular membranes. An experimentally
constrained multiscale model shows that a minimal branched actin network is sufficient to …

When stiffness matters: mechanosensing in heart development and disease

R Gaetani, EA Zizzi, MA Deriu, U Morbiducci… - Frontiers in Cell and …, 2020 - frontiersin.org
During embryonic morphogenesis, the heart undergoes a complex series of cellular
phenotypic maturations (eg, transition of myocytes from proliferative to quiescent or …

Actin mechanics and fragmentation

M Enrique, ML Gardel - Journal of Biological Chemistry, 2015 - ASBMB
Cell physiological processes require the regulation and coordination of both mechanical
and dynamical properties of the actin cytoskeleton. Here we review recent advances in …

Supramolecular dissipative self‐assembly systems: Approaches and applications

XF Hou, X Chen, JH Wei, Y Xu, XM Chen… - Responsive …, 2023 - Wiley Online Library
Dissipative self‐assembly (DSA) system requires a continuous supply of fuels to maintain
the far‐from‐equilibrium assembled state. Living organisms exist and operate far from the …

Directional spread of alphaherpesviruses in the nervous system

T Kramer, LW Enquist - Viruses, 2013 - mdpi.com
Alphaherpesviruses are pathogens that invade the nervous systems of their mammalian
hosts. Directional spread of infection in the nervous system is a key component of the viral …

Allosteric activation of T cell antigen receptor signaling by quaternary structure relaxation

AL Lanz, G Masi, N Porciello, A Cohnen, D Cipria… - Cell reports, 2021 - cell.com
The mechanism of T cell antigen receptor (TCR-CD3) signaling remains elusive. Here, we
identify mutations in the transmembrane region of TCRβ or CD3ζ that augment peptide …

The ParMRC system: molecular mechanisms of plasmid segregation by actin-like filaments

J Salje, P Gayathri, J Löwe - Nature Reviews Microbiology, 2010 - nature.com
The ParMRC plasmid partitioning apparatus is one of the best characterized systems for
bacterial DNA segregation. Bundles of actin-like filaments are used to push plasmids to …