Candida parapsilosis: from genes to the bedside
R Tóth, J Nosek, HM Mora-Montes… - Clinical microbiology …, 2019 - Am Soc Microbiol
Patients with suppressed immunity are at the highest risk for hospital-acquired infections.
Among these, invasive candidiasis is the most prevalent systemic fungal nosocomial …
Among these, invasive candidiasis is the most prevalent systemic fungal nosocomial …
Candida albicans, a major human fungal pathogen
Candida albicans is the most common human fungal pathogen (Beck-Sague and Jarvis,
1993). It is normally a harmless commensal organism. However, it is a opportunistic …
1993). It is normally a harmless commensal organism. However, it is a opportunistic …
Systematic screens of a Candida albicans homozygous deletion library decouple morphogenetic switching and pathogenicity
Candida albicans is the most common cause of serious fungal disease in humans. Creation
of isogenic null mutants of this diploid organism, which requires sequential gene targeting …
of isogenic null mutants of this diploid organism, which requires sequential gene targeting …
F901318 represents a novel class of antifungal drug that inhibits dihydroorotate dehydrogenase
JD Oliver, GEM Sibley, N Beckmann… - Proceedings of the …, 2016 - National Acad Sciences
There is an important medical need for new antifungal agents with novel mechanisms of
action to treat the increasing number of patients with life-threatening systemic fungal disease …
action to treat the increasing number of patients with life-threatening systemic fungal disease …
Hydrolytic enzymes as virulence factors of Candida albicans
M Schaller, C Borelli, HC Korting, B Hube - Mycoses, 2005 - Wiley Online Library
Candida albicans is a facultative pathogenic micro‐organism that has developed several
virulence traits enabling invasion of host tissues and avoidance of host defence …
virulence traits enabling invasion of host tissues and avoidance of host defence …
[HTML][HTML] Immune sensing of Candida albicans requires cooperative recognition of mannans and glucans by lectin and Toll-like receptors
The fungal pathogen Candida albicans has a multilayered cell wall composed of an outer
layer of proteins glycosylated with N-or O-linked mannosyl residues and an inner skeletal …
layer of proteins glycosylated with N-or O-linked mannosyl residues and an inner skeletal …
Candida albicans mannans mediate Streptococcus mutans exoenzyme GtfB binding to modulate cross-kingdom biofilm development in vivo
Candida albicans is frequently detected with heavy infection by Streptococcus mutans in
plaque-biofilms from children with early-childhood caries (ECC). This cross-kingdom biofilm …
plaque-biofilms from children with early-childhood caries (ECC). This cross-kingdom biofilm …
Strains and Strategies for Large-Scale Gene Deletion Studies of the Diploid Human Fungal Pathogen Candida albicans
SM Noble, AD Johnson - Eukaryotic cell, 2005 - Am Soc Microbiol
Candida albicans is the most common human fungal pathogen and causes significant
morbidity and mortality worldwide. Nevertheless, the basic principles of C. albicans …
morbidity and mortality worldwide. Nevertheless, the basic principles of C. albicans …
Fungal chitin dampens inflammation through IL-10 induction mediated by NOD2 and TLR9 activation
Chitin is an essential structural polysaccharide of fungal pathogens and parasites, but its
role in human immune responses remains largely unknown. It is the second most abundant …
role in human immune responses remains largely unknown. It is the second most abundant …
From Attachment to Damage: Defined Genes of Candida albicans Mediate Adhesion, Invasion and Damage during Interaction with Oral …
Candida albicans frequently causes superficial infections by invading and damaging
epithelial cells, but may also cause systemic infections by penetrating through epithelial …
epithelial cells, but may also cause systemic infections by penetrating through epithelial …