Assessing the risk of second malignancies after modern radiotherapy

WD Newhauser, M Durante - Nature Reviews Cancer, 2011 - nature.com
Recent advances in radiotherapy have enabled the use of different types of particles, such
as protons and heavy ions, as well as refinements to the treatment of tumours with standard …

Models for exposure-time-response relationships with applications to cancer epidemiology

DC Thomas - Annual review of public health, 1988 - hero.epa.gov
Time related factors in exposure/response relationships in chronic disease epidemiology
were discussed. Reasons for examining temporal factors in studies chronic disease were …

[HTML][HTML] Observation of decreased radiation damage at higher dose rates in room temperature protein crystallography

RJ Southworth-Davies, MA Medina, I Carmichael… - Structure, 2007 - cell.com
Radiation damage can be a problem when utilizing ionizing X-radiation in macromolecular
crystallography. The dose dependence of radiation damage to eight lysozyme crystals at …

Transformation of human osteoblast cells to the tumorigenic phenotype by depleted uranium-uranyl chloride.

AC Miller, WF Blakely, D Livengood… - Environmental …, 1998 - ehp.niehs.nih.gov
Depleted uranium (DU) is a dense heavy metal used primarily in military applications.
Although the health effects of occupational uranium exposure are well known, limited data …

Neoplastic cell transformation by heavy charged particles

TCH Yang, LM Craise, MT Mei… - Radiation …, 1985 - meridian.allenpress.com
With confluent cultures of the C3H10T1/2 mammalian cell line, we have investigated the
effects of heavy-ion radiation on neoplastic cell transformation. Our quantitative data …

Neoplastic transformation of human osteoblast cells to the tumorigenic phenotype by heavy metal–tungsten alloy particles: induction of genotoxic effects

AC Miller, S Mog, LA McKinney, L Luo, J Allen… - …, 2001 - academic.oup.com
Heavy metal–tungsten alloys (HMTAs) are dense heavy metal composite materials used
primarily in military applications. HMTAs are composed of a mixture of tungsten (91–93%) …

Repair processes in radiation biology

MM Elkind - Radiation research, 1984 - meridian.allenpress.com
Three dualities underscore the role of repair in radiobiology: the discrete and random nature
of energy deposition; the coupled processes of damage and repair; and the harmful and …

Dose and dose rate extrapolation factors for malignant and non-malignant health endpoints after exposure to gamma and neutron radiation

V Tran, MP Little - Radiation and environmental biophysics, 2017 - Springer
Murine experiments were conducted at the JANUS reactor in Argonne National Laboratory
from 1970 to 1992 to study the effect of acute and protracted radiation dose from gamma …

Genetic, cytogenetic, and carcinogenic effects of radon: a review

RF Jostes - Mutation Research/Reviews in Genetic Toxicology, 1996 - Elsevier
Radon exposure has been linked to lung carcinogenesis in both human and animal studies.
Studies of smoking and nonsmoking uranium miners indicate that radon alone is a risk factor …

The impact of dose rate on DNA double-strand break formation and repair in human lymphocytes exposed to fast neutron irradiation

S Nair, M Engelbrecht, X Miles, R Ndimba… - International Journal of …, 2019 - mdpi.com
The lack of information on how biological systems respond to low-dose and low dose-rate
exposures makes it difficult to accurately assess the carcinogenic risks. This is of critical …