Neurological complications and infection mechanism of SARS-COV-2

D Wan, T Du, W Hong, L Chen, H Que, S Lu… - Signal Transduction and …, 2021 - nature.com
Abstract Currently, SARS-CoV-2 has caused a global pandemic and threatened many lives.
Although SARS-CoV-2 mainly causes respiratory diseases, growing data indicate that SARS …

Angiotensin II signal transduction: an update on mechanisms of physiology and pathophysiology

SJ Forrester, GW Booz, CD Sigmund… - Physiological …, 2018 - journals.physiology.org
The renin-angiotensin-aldosterone system plays crucial roles in cardiovascular physiology
and pathophysiology. However, many of the signaling mechanisms have been unclear. The …

[HTML][HTML] ACE2, much more than just a receptor for SARS-COV-2

L Samavati, BD Uhal - Frontiers in cellular and infection microbiology, 2020 - frontiersin.org
The rapidly evolving pandemic of severe acute respiratory syndrome coronavirus (SARS-
CoV-2) infection worldwide cost many lives. The angiotensin converting enzyme-2 (ACE-2) …

SARS-CoV-2 Entry Receptor ACE2 Is Expressed on Very Small CD45 Precursors of Hematopoietic and Endothelial Cells and in Response to Virus Spike Protein …

MZ Ratajczak, K Bujko, A Ciechanowicz… - Stem cell reviews and …, 2021 - Springer
Abstract Angiotensin-converting enzyme 2 (ACE2) plays an important role as a member of
the renin–angiotensin–aldosterone system (RAAS) in regulating the conversion of …

Brain renin–angiotensin system at the intersect of physical and cognitive frailty

C Cosarderelioglu, LS Nidadavolu… - Frontiers in …, 2020 - frontiersin.org
The renin–angiotensin system (RAS) was initially considered to be part of the endocrine
system regulating water and electrolyte balance, systemic vascular resistance, blood …

Role of vitamin D in cardiovascular diseases

V Condoleo, C Pelaia, G Armentaro, G Severini… - Endocrines, 2021 - mdpi.com
Vitamin D represents a group of secosteroids involved in the calcium and phosphate
metabolism. The active form of vitamin D, 1, 25-dihydroxylcalciferol, exerts its biological …

COVID-19 and the renin-angiotensin system (RAS): A spark that sets the forest alight?

OJ Wiese, BW Allwood, AE Zemlin - Medical hypotheses, 2020 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) pandemic has increased exponentially
in numbers with more than 20 million people infected around the globe. It is clear that …

Elucidating the neuropathologic mechanisms of SARS-CoV-2 infection

M Pacheco-Herrero, LO Soto-Rojas… - Frontiers in …, 2021 - frontiersin.org
The current pandemic caused by the new severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) has become a public health emergency. To date, March 1, 2021, coronavirus …

The renin–angiotensin system: a possible new target for depression

J Vian, C Pereira, V Chavarria, C Köhler, B Stubbs… - BMC medicine, 2017 - Springer
Depression remains a debilitating condition with an uncertain aetiology. Recently, attention
has been given to the renin–angiotensin system. In the central nervous system, angiotensin …

Targeting renin–angiotensin system against Alzheimer's disease

AK Gebre, BM Altaye, TM Atey, KB Tuem… - Frontiers in …, 2018 - frontiersin.org
Renin Angiotensin System (RAS) is a hormonal system that regulates blood pressure and
fluid balance through a coordinated action of renal, cardiovascular, and central nervous …