Innovative drug delivery strategies for targeting glioblastoma: overcoming the challenges of the tumor microenvironment
Introduction Glioblastoma multiforme (GBM) presents a challenging endeavor in therapeutic
management because of its highly aggressive tumor microenvironment (TME). This complex …
management because of its highly aggressive tumor microenvironment (TME). This complex …
[HTML][HTML] Comparison of Drug Delivery Systems with Different Types of Nanoparticles in Terms of Cellular Uptake and Responses in Human Endothelial Cells …
Background/Objectives: The key components of the blood–brain barrier (BBB) are
endothelial cells, pericytes, astrocytes, and the capillary basement membrane. The BBB …
endothelial cells, pericytes, astrocytes, and the capillary basement membrane. The BBB …
Indomethacin-encapsulated PLGA nanoparticles improve therapeutic efficacy by increasing apoptosis and reducing motility in glioblastoma cells
Glioblastoma, with a low survival rate, is an aggressive and difficult-to-treat lethal type of
brain cancer. Indomethacin (IND), a non-steroidal anti-inflammatory drug, has antitumoral …
brain cancer. Indomethacin (IND), a non-steroidal anti-inflammatory drug, has antitumoral …