Bone injuries and diseases constitute a burden both socially and economically, as the
consequences of a lack of effective treatments affect both the patients' quality of life and the …

Bisphosphonates (BPs) are the most utilized drugs for the treatment of osteoporosis, and are
usefully employed also for other pathologies characterized by abnormally high bone …

The novelty of the present research consists in the possibility of obtaining cerium-doped
hydroxyapatite/collagen coatings on the titanium support, to improve the performance of the …

Bone cancer is usually a metastatic disease, affecting people of all ages. Its effective therapy
requires a targeted drug administration locally at the cancer site so that the surrounding …

The development of novel materials and approaches for effective energy consumption and
the employment of renewable energy sources is one of the current trends in modern material …

In the case of orthopedic and dental interventions, local antibiotic therapy reduces
significantly the risk associated with the intervention. The aim of this study was the …

The use of smart scaffolds with drug release capabilities is now widely recognized as a key
approach in designing hard tissue substitutes. In this study, alendronate sodium (AL) was …

The current study used the precipitation method to prepare pure calcium hydroxyapatite
(HA) and cerium-substituted hydroxyapatite (Ce-HA) nanoparticles, where cerium ions were …

Three dimensional (3D) scaffolds have huge limitations due to their low porosity, mechanical
strength, and lack of direct cell‐bioactive drug contact. Whereas bisphosphonate drug has …

To obtain a high-performance poly (lactide-co-glycolide)(PLGA)-based composite, a novel
functionalized hybrid nanohyoxyapatite (n-HA) was proposed by introducing carboxymethyl …