The biologically relevant coordination chemistry of iron and nitric oxide: electronic structure and reactivity

N Lehnert, E Kim, HT Dong, JB Harland… - Chemical …, 2021 - ACS Publications
Nitric oxide (NO) is an important signaling molecule that is involved in a wide range of
physiological and pathological events in biology. Metal coordination chemistry, especially …

Oxygen activation and radical transformations in heme proteins and metalloporphyrins

X Huang, JT Groves - Chemical reviews, 2017 - ACS Publications
As a result of the adaptation of life to an aerobic environment, nature has evolved a panoply
of metalloproteins for oxidative metabolism and protection against reactive oxygen species …

Sources of vascular nitric oxide and reactive oxygen species and their regulation

J Tejero, S Shiva, MT Gladwin - Physiological reviews, 2019 - journals.physiology.org
Nitric oxide (NO) is a small free radical with critical signaling roles in physiology and
pathophysiology. The generation of sufficient NO levels to regulate the resistance of the …

Current advances of nitric oxide in cancer and anticancer therapeutics

J Mintz, A Vedenko, O Rosete, K Shah, G Goldstein… - Vaccines, 2021 - mdpi.com
Nitric oxide (NO) is a short-lived, ubiquitous signaling molecule that affects numerous critical
functions in the body. There are markedly conflicting findings in the literature regarding the …

Structure and function of haemoglobins

DA Gell - Blood Cells, Molecules, and Diseases, 2018 - Elsevier
Haemoglobin (Hb) is widely known as the iron-containing protein in blood that is essential
for O 2 transport in mammals. Less widely recognised is that erythrocyte Hb belongs to a …

Dynamic Gut Microbiome across Life History of the Malaria Mosquito Anopheles gambiae in Kenya

Y Wang, TM Gilbreath III, P Kukutla, G Yan, J Xu - PloS one, 2011 - journals.plos.org
The mosquito gut represents an ecosystem that accommodates a complex, intimately
associated microbiome. It is increasingly clear that the gut microbiome influences a wide …

The clinical sequelae of intravascular hemolysis and extracellular plasma hemoglobin: a novel mechanism of human disease

RP Rother, L Bell, P Hillmen, MT Gladwin - Jama, 2005 - jamanetwork.com
ContextThe efficient sequestration of hemoglobin by the red blood cell membrane and the
presence of multiple hemoglobin clearance mechanisms suggest a critical need to prevent …

Triangle Cl−Ag1−Cl Sites for Superior Photocatalytic Molecular Oxygen Activation and NO Oxidation of BiOCl

F Guo, C Mao, C Liang, P Xing, L Yu… - Angewandte Chemie …, 2023 - Wiley Online Library
BiOCl photocatalysis shows great promise for molecular oxygen activation and NO
oxidation, but its selective transformation of NO to immobilized nitrate without toxic NO2 …

Oxidative stress

G Storz, JA Imlayt - Current opinion in microbiology, 1999 - Elsevier
Much has been learnt about oxidative stress from studies of Escherichia coli. Key regulators
of the adaptive responses in this organism are the SoxRS and OxyR transcription factors …

Reactive oxygen and nitrogen intermediates in the relationship between mammalian hosts and microbial pathogens

C Nathan, MU Shiloh - … of the National Academy of Sciences, 2000 - National Acad Sciences
This review summarizes recent evidence from knock-out mice on the role of reactive oxygen
intermediates and reactive nitrogen intermediates (RNI) in mammalian immunity. Reflections …