The art of building small: from molecular switches to motors (Nobel Lecture)

BL Feringa - Angewandte Chemie-International Edition, 2017 - research.rug.nl
A journey into the nano-world: The ability to design, use and control motor-like functions at
the molecular level sets the stage for numerous dynamic molecular systems. In his Nobel …

[HTML][HTML] Artificial molecular machines

S Erbas-Cakmak, DA Leigh, CT McTernan… - Chemical …, 2015 - ACS Publications
The widespread use of molecular machines in biology has long suggested that great
rewards could come from bridging the gap between synthetic molecular systems and the …

Synthetic molecular motors and mechanical machines

ER Kay, DA Leigh, F Zerbetto - … Chemie International Edition, 2007 - Wiley Online Library
The widespread use of controlled molecular‐level motion in key natural processes suggests
that great rewards could come from bridging the gap between the present generation of …

Ultrasonic control of neural activity through activation of the mechanosensitive channel MscL

J Ye, S Tang, L Meng, X Li, X Wen, S Chen, L Niu… - Nano …, 2018 - ACS Publications
Externally controlling the excitation of a neuronal subset through ion channels activation can
modulate the firing pattern of an entire neural circuit in vivo. As nanovalves in the cell …

Mechanosensitive channels: what can they do and how do they do it?

ES Haswell, R Phillips, DC Rees - Structure, 2011 - cell.com
While mechanobiological processes employ diverse mechanisms, at their heart are force-
induced perturbations in the structure and dynamics of molecules capable of triggering …

The art of building small: from molecular switches to molecular motors

BL Feringa - The Journal of organic chemistry, 2007 - ACS Publications
Molecular switches and motors are essential components of artificial molecular machines. In
this perspective, we discuss progress in our design, synthesis, and functioning of …

Hypoxic tumor microenvironment: Opportunities to develop targeted therapies

A Patel, S Sant - Biotechnology advances, 2016 - Elsevier
In recent years, there has been great progress in the understanding of tumor biology and its
surrounding microenvironment. Solid tumors create regions with low oxygen levels …

Inorganic nanomaterials for chemo/photothermal therapy: a promising horizon on effective cancer treatment

M Khafaji, M Zamani, M Golizadeh, O Bavi - Biophysical reviews, 2019 - Springer
During the last few decades, nanotechnology has established many essential applications
in the biomedical field and in particular for cancer therapy. Not only can nanodelivery …

The MscS and MscL families of mechanosensitive channels act as microbial emergency release valves

IR Booth, P Blount - Journal of bacteriology, 2012 - Am Soc Microbiol
Single-celled organisms must survive exposure to environmental extremes. Perhaps one of
the most variable and potentially life-threatening changes that can occur is that of a rapid …

Ion channels in microbes

B Martinac, Y Saimi, C Kung - Physiological reviews, 2008 - journals.physiology.org
Studies of ion channels have for long been dominated by the animalcentric, if not
anthropocentric, view of physiology. The structures and activities of ion channels had …