Pathogenesis and virulence of Candida albicans

JP Lopes, MS Lionakis - Virulence, 2022 - Taylor & Francis
Candida albicans is a commensal yeast fungus of the human oral, gastrointestinal, and
genital mucosal surfaces, and skin. Antibiotic-induced dysbiosis, iatrogenic …

The impact of the Fungus-Host-Microbiota interplay upon Candida albicans infections: current knowledge and new perspectives

C d'Enfert, AK Kaune, LR Alaban… - FEMS microbiology …, 2021 - academic.oup.com
Candida albicans is a major fungal pathogen of humans. It exists as a commensal in the oral
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …

[HTML][HTML] Invasive candidiasis

PG Pappas, MS Lionakis, MC Arendrup… - Nature Reviews …, 2018 - nature.com
Invasive candidiasis is an important health-care-associated fungal infection that can be
caused by several Candida spp.; the most common species is Candida albicans, but the …

[HTML][HTML] Vulvovaginal candidiasis: a current understanding and burning questions

HME Willems, SS Ahmed, J Liu, Z Xu, BM Peters - Journal of Fungi, 2020 - mdpi.com
Candida albicans, along with other closely related Candida species, are the primary
causative agents of vulvovaginal candidiasis (VVC)—a multifactorial infectious disease of …

Fungal microbiota dysbiosis in IBD

H Sokol, V Leducq, H Aschard, HP Pham, S Jegou… - Gut, 2017 - gut.bmj.com
Objective The bacterial intestinal microbiota plays major roles in human physiology and
IBDs. Although some data suggest a role of the fungal microbiota in IBD pathogenesis, the …

Vulvovaginal candidiasis: Epidemiology, microbiology and risk factors

B Gonçalves, C Ferreira, CT Alves… - Critical reviews in …, 2016 - Taylor & Francis
Vulvovaginal candidiasis (VVC) is an infection caused by Candida species that affects
millions of women every year. Although Candida albicans is the main cause of VVC, the …

Innate immune pattern recognition: a cell biological perspective

SW Brubaker, KS Bonham, I Zanoni… - Annual review of …, 2015 - annualreviews.org
Receptors of the innate immune system detect conserved determinants of microbial and viral
origin. Activation of these receptors initiates signaling events that culminate in an effective …

[HTML][HTML] Fungal microbiome in inflammatory bowel disease: a critical assessment

DM Underhill, J Braun - The Journal of Clinical Investigation, 2022 - Am Soc Clin Investig
The gut microbiome is at the center of inflammatory bowel disease (IBD) pathogenesis and
disease activity. While this has mainly been studied in the context of the bacterial …

[HTML][HTML] Immune defence against Candida fungal infections

MG Netea, LAB Joosten, JWM Van Der Meer… - Nature Reviews …, 2015 - nature.com
The immune response to Candida species is shaped by the commensal character of the
fungus. There is a crucial role for discerning between colonization and invasion at mucosal …

Guideline: vulvovaginal candidosis (AWMF 015/072, level S2k)

A Farr, I Effendy, B Frey Tirri, H Hof, P Mayser… - Mycoses, 2021 - Wiley Online Library
Abstract Approximately 70‐75% of women will have vulvovaginal candidosis (VVC) at least
once in their lifetime. In premenopausal, pregnant, asymptomatic and healthy women and …