Glycosylation is a prevalent, yet heterogeneous modification with a broad range of
implications in molecular biology. This heterogeneity precludes enrichment strategies that …

Sample preparation for mass spectrometry‐based proteomics has many tedious and time‐
consuming steps that can introduce analytical errors. In particular, the steps around the …

High‐throughput and streamlined workflows are essential in clinical proteomics for
standardized processing of samples from a variety of sources, including fresh‐frozen tissue …

Complete, reproducible extraction of protein material is essential for comprehensive and
unbiased proteome analyses. A current gold standard is single-pot, solid-phase-enhanced …

While LC-MS-based proteomics with high nanograms to micrograms of total protein has
become routine, the analysis of samples derived from low cell numbers is challenged by …

According to the 2020 Metrics of the HUPO Human Proteome Project (HPP), expression has
now been detected at the protein level for> 90% of the 19 773 predicted proteins coded in …

Performing large-scale plasma proteome profiling is challenging due to limitations imposed
by lengthy preparation and instrument time. We present a fully automated multiplexed …

Nowadays, massive genomics and transcriptomics data can be generated at the single-cell
level. However, proteomics in this setting is still a big challenge. Despite the great …

Cardiac cell surface proteins are drug targets and useful biomarkers for discriminating
among cellular phenotypes and disease states. Here we developed an analytical platform …

Routine measurement of cancer biomarkers is performed for early detection, risk
classification, and treatment monitoring, among other applications, and has substantially …