Cancer is the second cause of death worldwide, surpassed only by cardiovascular diseases,
due to the lack of early diagnosis, and high relapse rate after conventional therapies …

Cancer is one of the most leading causes of mortalities worldwide. It is caused by the
accumulation of genetic and epigenetic alterations in two types of genes: tumor suppressor …

As extracellular vesicles secreted by cells, exosomes are intercellular signalosomes for cell
communication and pharmacological effectors. Because of their special properties, including …

Human glioblastoma is the most aggressive type of primary malignant brain tumors.
Standard treatment includes surgical resection followed by radiation and chemotherapy but …

Human-induced pluripotent stem cells (hiPSCs) and CRISPR/Cas9 gene editing system
represent two instruments of basic and translational research, which both allow to acquire …

With the economy's globalization and the population's aging, cancer has become the
leading cause of death in most countries. While imposing a considerable burden on society …

Spinal cord injury (SCI) is a devastating and complicated condition with no cure available.
The initial mechanical trauma is followed by a secondary injury characterized by …

With the expansion of the microbiology field of research, a new genome editing tool arises
from the biology of bacteria that holds the promise of achieving precise modifications in the …

Epigenetic modulation can affect the characteristics of cancers. Because it is likely to
manipulate epigenetic genes, they can be considered as potential targets for cancer …

Glioblastoma (GBM) is the most invasive and devastating primary brain tumor with a median
overall survival rate about 18 months with aggressive multimodality therapy. Its unique …