IL-6 and IL-8: an overview of their roles in healthy and pathological pregnancies

A Vilotić, M Nacka-Aleksić, A Pirković… - International journal of …, 2022 - mdpi.com
Interleukin-6 (IL-6) is an acknowledged inflammatory cytokine with a pleiotropic action,
mediating innate and adaptive immunity and multiple physiological processes, including …

[HTML][HTML] Association of pregnancy with Coronavirus cytokine storm: systematic review and meta-analysis

J Muthuka, M Kiptoo, K Oluoch, JM Nzioki… - JMIR Pediatrics and …, 2022 - pediatrics.jmir.org
Background: COVID-19 was first identified in Wuhan, China, in December 2019, spreading
to the rest of the globe, becoming a pandemic. Some studies have shown an association …

Differentially expressed circulating microRNAs associated with idiopathic recurrent pregnancy loss

DS Jairajpuri, ZH Malalla, N Mahmood, F Khan… - Gene, 2021 - Elsevier
Recurrent pregnancy loss (RPL) is a major pregnancy complication which reportedly affects
2–3% of all pregnancies. Currently, RPL lacks an effective therapy and a reliable diagnostic …

Decreased production of TNF-α and IL-6 inflammatory cytokines in non-pregnant idiopathic RPL women immunomodulatory effect of sildenafil citrate on the cellular …

M Kniotek, M Zych, A Roszczyk, M Szafarowska… - Journal of Clinical …, 2021 - mdpi.com
Sildenafil citrate (SC), a PDE5 inhibitor, a drug for erectile dysfunction (ED) and pulmonary
hypertension (PAH), was found to exert a positive effect on pregnancy outcomes when …

Association of reduced maternal sHLA‐G5 isoform levels and elevated TNF‐α/IL‐4 cytokine ratio with Recurrent Pregnancy Loss: A study on South Indian women

D Madduru, K Dirsipam, M Goli… - Scandinavian …, 2021 - Wiley Online Library
Inflammation is of critical importance in successful implantation during pregnancy. However,
the establishment of maternal immune tolerance towards semi‐allograft foetus is more …

Immunophenotyping of peripheral blood monocytes could help identify a baseline pro-inflammatory profile in women with recurrent reproductive failure

A Comins-Boo, L Valdeolivas, F Pérez-Pla… - Journal of Reproductive …, 2022 - Elsevier
Recurrent pregnancy loss (RPL) and recurrent implantation failure (RIF) are two well-
defined clinical entities, but the role of the monocytes in their pathophysiology needs to be …

A comparative study on various immunological parameters influencing embryo survivability in crossbred dairy cows

BSK Panda, SK Mohapatra, AK Verma, A Kamboj… - Theriogenology, 2020 - Elsevier
Since long embryonic mortality has remained an area of concern affecting the reproduction,
production, and profitability of dairy cows. We investigated the possible interaction between …

The Impact of Inflammatory Cytokines on Recurrent Pregnancy Loss: A Preliminary Investigation

S Mishra, A Ashish, S Rai, C Sahni, S Tiwari… - Reproductive …, 2025 - Springer
Recurrent pregnancy loss (RPL), defined as two or more consecutive miscarriages before
20 weeks of gestation, affects 1–2% of couples worldwide. Pro-inflammatory cytokines, such …

[HTML][HTML] Understanding the potential immunogenetic role of TNFα-308 polymorphism in the pathogenesis of recurrent miscarriage

S Ali, S Majid, MN Ali, MZ Banday, S Taing - Heliyon, 2023 - cell.com
Background Recurrent miscarriage (RM) represents the spontaneous termination of two or
more successive pregnancies. TNFα is a proinflammatory cytokine that is often considered …

IL-6 and IL-8: An Overview of Their Roles in Healthy and Pathological Pregnancies

A Vilotic, M Nacka-Aleksic, A Pirkovic… - Int. J. Mol. Sci, 2022 - europepmc.org
Abstract Interleukin-6 (IL-6) is an acknowledged inflammatory cytokine with a pleiotropic
action, mediating innate and adaptive immunity and multiple physiological processes …