A Compressive Review about Taxol®: History and Future Challenges

J Gallego-Jara, G Lozano-Terol, RA Sola-Martínez… - Molecules, 2020 - mdpi.com
Taxol®, which is also known as paclitaxel, is a chemotherapeutic agent widely used to treat
different cancers. Since the discovery of its antitumoral activity, Taxol® has been used to …

Pharmaceutical formulations with P-glycoprotein inhibitory effect as promising approaches for enhancing oral drug absorption and bioavailability

TTL Nguyen, VA Duong, HJ Maeng - Pharmaceutics, 2021 - mdpi.com
P-glycoprotein (P-gp) is crucial in the active transport of various substrates with diverse
structures out of cells, resulting in poor intestinal permeation and limited bioavailability …

BCS class IV drugs: Highly notorious candidates for formulation development

R Ghadi, N Dand - Journal of Controlled Release, 2017 - Elsevier
BCS class IV drugs (eg, amphotericin B, furosemide, acetazolamide, ritonavir, paclitaxel)
exhibit many characteristics that are problematic for effective oral and per oral delivery …

Emerging research and clinical development trends of liposome and lipid nanoparticle drug delivery systems

JC Kraft, JP Freeling, Z Wang, RJY Ho - Journal of pharmaceutical …, 2014 - Elsevier
Liposomes are spherical-enclosed membrane vesicles mainly constructed with lipids. Lipid
nanoparticles are loaded with therapeutics and may not contain an enclosed bilayer. The …

Oral delivery of anticancer drugs: challenges and opportunities

K Thanki, RP Gangwal, AT Sangamwar… - Journal of controlled …, 2013 - Elsevier
The present report focuses on the various aspects of oral delivery of anticancer drugs. The
significance of oral delivery in cancer therapeutics has been highlighted which principally …

Self-emulsifying drug delivery systems (SEDDS) for improved oral delivery of lipophilic drugs

RN Gursoy, S Benita - Biomedicine & pharmacotherapy, 2004 - Elsevier
The oral delivery of hydrophobic drugs presents a major challenge because of the low
aqueous solubility of such compounds. Self-emulsifying drug delivery systems (SEDDS) …

Self-microemulsifying drug delivery system (SMEDDS)–challenges and road ahead

S Dokania, AK Joshi - Drug delivery, 2015 - Taylor & Francis
Self-microemulsifying drug delivery system (SMEDDS) has emerged as a vital strategy to
formulate poor water soluble compounds for bioavailability enhancement. However, certain …

[图书][B] Microencapsulation: methods and industrial applications

S Benita - 2005 - taylorfrancis.com
Presenting breakthrough research pertinent to scientists in a wide range of disciplines-from
medicine and biotechnology to cosmetics and pharmacy-this Second Edition provides …

Self-emulsifying drug delivery systems: an approach to enhance oral bioavailability

K Kohli, S Chopra, D Dhar, S Arora, RK Khar - Drug discovery today, 2010 - Elsevier
Self-emulsifying drug delivery systems are a vital tool in solving low bioavailability issues of
poorly soluble drugs. Hydrophobic drugs can be dissolved in these systems, enabling them …

Self-emulsifying drug delivery systems (SEDDS): formulation development, characterization, and applications

B Singh, S Bandopadhyay, R Kapil… - Critical Reviews™ in …, 2009 - dl.begellhouse.com
Self-emulsifying drug delivery systems (SEDDS) possess unparalleled potential in
improving oral bioavailability of poorly water-soluble drugs. Following their oral …