Hyperglycemia and oxidative stress: An integral, updated and critical overview of their metabolic interconnections

P González, P Lozano, G Ros, F Solano - International Journal of …, 2023 - mdpi.com
This review focuses on the multiple and reciprocal relationships that exist between oxidative
stress, hyperglycemia and diabetes and related metabolic disorders. Human metabolism …

Targeting PPARs for therapy of atherosclerosis: A review

M Miao, X Wang, T Liu, YJ Li, WQ Yu, TM Yang… - International journal of …, 2023 - Elsevier
Atherosclerosis, a chief pathogenic factor of cardiovascular disease, is associated with many
factors including inflammation, dyslipidemia, and oxidative stress. Peroxisome proliferator …

Modulatory effect of lifestyle-related, environmental and genetic factors on paraoxonase-1 activity: a review

D Kunachowicz, M Ściskalska, M Kepinska - International Journal of …, 2023 - mdpi.com
Paraoxonase-1 (PON1) is a calcium-dependent, HDL-bound serum hydrolase active toward
a wide variety of substrates. PON1 displays three types of activities, among which lactonase …

Development of functional noodles by encapsulating mango peel powder as a source of bioactive compounds

MR Kabir, SMK Hasan, MR Islam, M Ahmed - Heliyon, 2024 - cell.com
Antioxidant compounds such as phenolics and carotenoids scavenge reactive oxygen
species and protect against degenerative diseases such as cancer and cardiovascular …

The Role of Polyphenols in Modulating PON1 Activity Regarding Endothelial Dysfunction and Atherosclerosis

TB Sirca, ME Mureșan, A Pallag, E Marian… - International Journal of …, 2024 - mdpi.com
The incidence and prevalence of cardiovascular diseases are still rising. The principal
mechanism that drives them is atherosclerosis, an affection given by dyslipidemia and a pro …

Protective Effects of Graptopetalum paraguayense E. Walther against Methylglyoxal-Induced Liver Damage and Microflora Imbalances Caused by High-Fructose …

BH Lee, SR Shen, PS Lee, XS Huang, WC Chang… - Fermentation, 2023 - mdpi.com
Methylglyoxal (MG) is a highly reactive dicarbonyl aldehyde and a major precursor of
advanced glycation end products that result in oxidative stress. Graptopetalum …

The Effect of Curcumin on Paraoxonase 1 Protein Levels, Gene expression, and Enzyme Activity: A Systematic Review of Animal Interventional Studies

F Hamedi-Kalajahi, M Alizadeh, R Molani-Gol… - Prostaglandins & Other …, 2024 - Elsevier
Abstract Background & Aims Paraoxonase (PON) proteins have various hydrolytic activities.
The PON family is able to detoxify oxidized low-density lipoprotein. Additionally …

Modulation of the antioxidant enzyme paraoxonase-1 for protection against cardiovascular diseases

W Dornas, M Silva - Nutrition, Metabolism and Cardiovascular Diseases, 2024 - Elsevier
Aim The enzyme paraoxonase 1 (PON1) bound to high-density lipoprotein has received
special attention for its protective role against stress-mediated damage and use as a …

Development of Nanoemulsions for Wound Dressings Containing Cassia alata L. Leaf Extraction

S Sangkaew, S Wanmasae… - Evidence‐Based …, 2022 - Wiley Online Library
Natural polymer‐based hydrogel films possess considerable potential for use in biomedical
applications and are excellent for wound healing. The purpose of this research was to use …

Hepatic dysmetabolism in polycystic ovarian syndrome: impact of paraoxonase-1 modulation by butyrate

SE Areloegbe, OA Oyekanmi, IO Ajadi, MB Ajadi… - Comparative Clinical …, 2024 - Springer
The complications of endocrine-metabolic disorders among women of reproductive age,
inclusively polycystic ovarian syndrome (PCOS), are cascade of events leading to …